CLAY | Contact Lens Assessment in Youth

 

CLAY Investigators

Robin L. Chalmers, OD (Clinical Trial Consultant, Atlanta, GA)
Meredith E. Jansen, OD MS (Research Optometrist, Indiana University College of Optometry)
Beth T. Kinoshita, OD (Assistant Professor, Pacific University College of Optometry)
Dawn Y. Lam, MSc OD (Assistant Professor, Southern California College of Optometry)
G. Lynn Mitchell, MAS (Assistant Professor, Ohio State University College of Optometry)
Kathryn Richdale, OD PhD (Assistant Professor, SUNY College of Optometry
Luigina Sorbara, OD MSc (Associate Professor, University of Waterloo School of Optometry)
Heidi Wagner, OD MPH (Professor, Nova Southeastern University College of Optometry)

Background

The Contact Lens Assessment in Youth (CLAY) team is comprised of cornea and contact lens researchers in academic centers across North America and was formed at the 2008 Summer Research Institute.

Support

The Summer Research Institute is made possible by the American Optometric Association (AOA) and the American Academy of Optometry (AAO). The AOA and AAO provide support for weekly conference calls and annual conference meeting rooms. Funding to conduct our research has been received via unrestricted grants from Alcon/CIBA Vision and a NOVA Southeastern University Chancellors Research and Development Grant: Health Professions Division Research Grant. These funds have been used for data collection and analysis, development of presentations and publications, and team meetings.

Research Question

The research question developed at the 2008 Summer Research Institute was: Is youth a risk factor for contact lens wear? Analysis of our initial retrospective chart review and prospective soft contact lens risk questionnaire has further developed our research aims to examine modifiable risk factors in teenage and young-adult contact lens wearers.

Published Manuscripts

Jansen ME, Chalmers RL, Mitchell GL, Kinoshita BT, Lam DY, McMahon TT, Richdale K, Sorbara L, Wagner H. Characterization of patients who report compliant and non-compliant overnight wear of soft contact lenses. Contact Lens and Anterior Eye (2011); 34:229-235.
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Lam DY, Kinoshita BT, Jansen ME, Mitchell GL, Chalmers RL, McMahon TT, Richdale K, Sorbara L, Wagner H as the CLAY Study Group. Contact lens assessment in youth (CLAY): methods and baseline findings. Optometry and Vision Science (2011); 88:708-715.
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Chalmers RL, Wagner H, Mitchell GL, Lam DY, Kinoshita BT, Jansen ME, Richdale K, Sorbara L, McMahon TT. Age and other risk factors for corneal infiltrative and inflammatory events in young soft contact lens wearers from the contact lens assessment in youth (CLAY) study. Investigative Ophthalmology and Vision Science (2011); 52:6690-6696.
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Wagner H, Chalmers R, Mitchell L, Jansen ME, Kinoshita BT, Lam DY, McMahon TT, Richdale K, Sorbara L. Risk factors for interruption to soft contact lens wear in youth. Optometry and Vision Science (2011); 88:973-980.
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National and International Conference Abstracts

ARVO 2010
Lam D, Kinoshita B, Jansen ME, Mitchell GL, Chalmers R, Richdale K, Sorbara L and Wagner H. Contact lens assessment in youth (CLAY) study design and baseline data. Investigative Ophthalmology and Vision Science (2010) E-abstract 1529/D820.

Chalmers RL, Wagner H, Mitchell GL, Jansen ME, Kinoshita BT, Lam D, Richdale K and Sorbara L. Age and other risk factors for serious & significant events with contact lens wear in youth. Investigative Ophthalmology and Vision Science (2010) E-abstract 1524/D815.

Wagner H, Chalmers RL, Mitchell GL, Jansen ME, Kinoshita BT, Lam D, Richdale K and Sorbara L. Age and events that interrupt contact lens wear in youth. Investigative Ophthalmology and Vision Science (2010) E-abstract 1510/D801.

Kinoshita BT, Lam D, Mitchell GL, Wagner H, Chalmers R, Jansen ME, Richdale K and Sorbara L. Distribution of baseline soft contact lens power by age in the CLAY study. Investigative Ophthalmology and Vision Science (2010) E-abstract 1512/D803.

BCLA 2010
Chalmers RL, Mitchell GL, Jansen ME, Kinoshita BT, Richdale K, Sorbara L. Age and other risk factors for serious and significant events with contact lens wear in youth. Contact Lens and Anterior Eye (2010) 33:280.

Sorbara L, Mitchell GL, Jansen ME, Kinoshita BT, Lam DY, Richdale K. The relationship between corneal fluorescein staining and corneal infiltrates with a change in care system in North American soft CL wearers. Contact Lens and Anterior Eye (2010) 33:282.

Richdale K, Mitchell GL, Jansen ME, Kinoshita BT, Sorbara L, Wagner H. Geographical and temporal aspects of contact lens complications in the CLAY study. Contact Lens and Anterior Eye (2010) 33:268.

Jansen ME, Chalmers RL, Mitchell GL, Richdale KL, Sorbara L, Lam DY. Characterization of patients wearing contact lenses on an extended wear (EW) basis, both in and out of US FDA EW indication. Contact Lens and Anterior Eye (2010) 33:267.

AAO 2010
Wagner H, Mitchell GL, Chalmers RL, Kinoshita BT, Jansen ME, Lam D, Richdale K and Sorbara L. Characteristics of and risk factors for multiple ocular events that interrupt soft CL wear in youth. Optometry and Vision Science (2010) 87: E-abstract 105855.

Chalmers RL, Wagner H, Mitchell GL, Kinoshita BT, Jansen ME, Lam D, Richdale K and Sorbara L. The role of overnight wear in corneal inflammatory events from the CLAY study. Optometry and Vision Science (2010) 87:E-abstract 100828.

Kinoshita BT, Mitchell GL, Lam D, Chalmers RL, Wagner H, Jansen ME, Richdale K and Sorbara L. Prescribing patterns of soft contact lens wear in North America. Optometry and Vision Science (2010) 87:E-abstract 100064.

ARVO 2011
Wagner H, Chalmers RL, Mitchell GL, Jansen ME, Kinoshita BT, Lam DY, McMahon TT, Richdale K, and Sorbara L. Gaps in contact lens case history: identifying items for a soft contact lens risk questionnaire. Investigative Ophthalmology and Vision Science (2011) E-abstract 6500/D964.

BCLA 2011
Kinoshita BT, Chalmers RL, Mitchell GL, Lam DY, Sorbara L, Jansen ME, McMahon TT. Unique characteristics of neophyte soft contact lens wearers in the contact lens assessment in youth (CLAY) study. Contact Lens and Anterior Eye (2011) 34:S7.

Lam DY, Chalmers RL, Mitchell GL, Kinoshita BT, Jansen ME, Wagner H. Gender differences in soft contact lens prescribing, wearing habits and patient retention in the CLAY Study. Contact Lens and Anterior Eye (2011) 34:S37.

ARVO 2012
Kinoshita BT, Chalmers RL, Mitchell GL, Jansen ME, Lam DY, McMahon TT, Richdale K, Sorbara L, Wagner H. Minus soft contact lens power progression in young myopes: a retrospective chart review. Investigative Ophthalmology and Vision Science (2012); E-abstract 4719/A30

BCLA 2012
Chalmers RL, Mitchell GL, Kinoshita BT, Wagner H, Jansen NE, Lam DY and Richdale K. Survey of the relationship between age, environmental exposures and general health status in young soft contact lens wearers. Contact Lens and Anterior Eye (2012) 35,1:e40.

Jansen ME, Wagner H, Kinoshita BT, Mitchell GL, Chalmers RL, Richdale K, and Lam DY. Survey of previously established risk behaviors in young soft contact lens wearers. Contact Lens and Anterior Eye (2012) 35, 1:e1-e2.

AAO 2012
Richdale K, Mitchell GL, Wagner H, Sorbara L, Lam DY, Kinoshita BT, Jansen ME, Chalmers RL. Development of a soft contact lens risk assessment survey. Optometry and Vision Science (2012) 89: E-abstract 120976.

Wagner H, Jansen ME, Mitchell GL, Kinoshita BT, Lam DY, Richdale K, Chalmers RL. Age-related differences in behavior, environmental factors and general health status. Optometry and Vision Science (2012) 89:E-abstract 125021.

Kinoshita BT and Jansen ME. CLAY: Transition from research to practice. Presented Wednesday, October 24, 2012, at 04:00 PM for one hour continuing education (Room 222 A-C), Phoenix Convention Center.

CLAY Study Team

Clinical Sites

Indiana University School of Optometry, Bloomington, IN:
Meredith E. Jansen, OD MS (Principal Investigator), Angelina Bonner (data entry 2009), Kristen Burkholder (data entry 2009 – 2010), Carolyn Masters (data entry 2009 –  2010), Samuel Hargus (survey data collection 2011 – present), Fraser McKay (survey data collection 2011 – present). 

Nova Southeastern University College of Optometry, Ft. Lauderdale, FL:
Heidi Wagner, OD MPH (Principal Investigator), Steven Warne (data entry 2009), Margi A. Patel (data entry and survey data collection 2009 – 2011), Maggie Lee (survey data collection 2011), Victoria Trieu (survey data collection 2011), Lindsey Vernillo (survey data collection 2011 – 2012), Amorette Hanna (survey data collection 2012).

Ohio State University College of Optometry, Columbus, OH:
Kathryn Richdale, OD MS (Principal Investigator 2009 – 2011), Austin L.Tanner (data entry 2009 – 2011)

Pacific University College of Optometry, Forest Grove, OR:
Beth T. Kinoshita, OD (Principal Investigator), Evelyn Y. Hu (data entry 2008), Firas Basha (survey data collection 2011), Breanne McLain (survey data collection 2011) Kate Dalrymple (survey data collection 2012), MacKenzie Macintyre III (survey data collection 2012), David Ruckman (survey data collection 2012).

Southern California College of Optometry, Fullerton, CA:
Dawn Y. Lam, MSc, OD (Principal Investigator); Jaime Lam (data entry 2009), Fabian Corona (survey data collection 2011 – 2012), Daniel Brinchman (survey data collection 2011 – 2012)

State University of New York College of Optometry, New York, NY:
Kathryn Richdale, OD PhD (Principal Investigator 2011 – present), Kerinna Coffey, BA (survey data collection 2011), Chelsea Stewart, BS (survey data collection 2011), Jessica Troilo (survey data collection 2012), Tyler Maxon, BA (survey data collection 2012)

University of Waterloo School of Optometry, Waterloo, ON, Canada:
Luigina Sorbara, OD, MSc (Principal Investigator); Gerry Giddens, HBSc (data entry 2009), Jyotsna Maram, PhD (data entry 2009)

Resource Centers

Data Coordinating Center
The Ohio State University College of Optometry, Columbus, OH: G. Lynn Mitchell, MAS (Director)

Event Data Management Center
Robin L. Chalmers, OD (Director); Julia Purser (data management 2009), Lucas Henneman (data management 2009)

Committees

Adjudication Team (2009)
Mark A. Bullimore, MCOptom, PhD; Robin L. Chalmers, OD; Timothy T. McMahon, OD; Heidi Wagner, OD, MPH

Consultant
Tim McMahon (2008 – 2012)

Executive Committee:
Heidi Wagner, OD, MPH (Co-Chair 2009 – present), Robin L. Chalmers, OD (Co-Chair 2009 – 2012); Kathryn Richdale, OD PhD (Co-Chair 2012 – present); G. Lynn Mitchell, MAS (2009 – present),

 

 

To contact the CLAY study group email KRichdale@SUNYopt.edu