Harry J. Wyatt, Ph.D (Professor Emeritus)
SUNY College of Optometry
33 West 42nd Street New York, NY 10036


Research Interests

 

Pupil function and the structure of the iris ( Iris Model | Sector Dilation Model )
Use of the pupillary light reflex to assess retinal status.
The use of visual information in controlling eye movements
Pharmacokinetics and fluid movement in the eye ( Movement of a substance applied to the eye )
Mechanics of accommodation
Tactile presentation of "visual" information

Education

 

Ph.D. (Biophysics) l97l, University of California, Berkeley
M.A. (Physics) l967, University of California, Berkeley
B.A. (Physics) l964, Pomona College

 

Professional Experience

 

Department of Biological Sciences, State College of Optometry, State University of New York (SUNY Distinguished Teaching Professor, 1993-2007 (Emeritus, 2007); Chair, 1988-94; Professor, 1984-93; Associate Professor, 1978-84; Assistant Professor, 1975-78)
Research Fellow, Department of Physiology & Biophysics, Washington University Medical School, St. Louis, Missouri, 1971-75 (National Institutes of Health Training Grant)
Teaching Associate, University of California, Berkeley, l967-68
Teaching Assistant, University of California, Berkeley, l964-66

 

 

 

Awards & Distinctions

 

Invited speaker, Gordon Research Conference on Theoretical Biology and Biomathematics, Tilton, New Hampshire, June 7-11, 1998.
SUNY Distinguished Teaching Professor, 1993.
SUNY Chancellor's Award for Excellence in Teaching, 1990.

Research Grants

 

NIH/NEI Grant R03EY014549 "A Rapid Pupillometric Test for Glaucoma", 2003-07. (P.I.)
NIH/NEI Grant 5T35EY007079 "Short Term Training Students –Health Professional Schools", Summer 2005, Summer 2006. (P.I.: K.J. Ciuffreda)
Langeloth Foundation Grant "Investigation of Tactile Alphabets and Clinical Protocols to aid in the Rehabilitation of the Visually Impaired" 2004, P.I. Kathy Aquilante (Role: Consultant)
Langeloth Foundation Grant "Investigation of a New Tactile Alphabet to Aid in the Rehabilitation of the Adventitiously Blind" 2000, P.I. William O’Connell (Role: Co-Investigator)
NIH/NEI Grant 5K23EY000394-05 "S Cone Responses And Neural Pathways For Accomodation", 1999-2004, P.I.: Frances Rucker (Role: Co-Investigator 2003-2004)
NIH/NEI Grant 5K23EY000366-04 "Reading Eye Movements in Nystagmus/Central Field Loss", 1998-2003, P.I.: Kathy Aquilante  (Role: Co-Investigator 1998-2000)
NIHNEI Grant 5R01MH047542 "Complex Dynamics And Noise In The Pupil Light Reflex", 1998-1999, P.I.: John Milton, University of Chicago (Role: Consultant)
Schnurmacher Institute for Vision Research, SUNY, "Normal and Abnormal Pupil Function", 1991-93; "The Mechanical Behavior of the Vitreous", 1993-94; "Form and Function of the Human Pupil", 1994-95; "Analysis of Pupil Dilation", 1995-96.   (Role: P.I.)
NSF Grant BNS -85-19267, Visual Control of Fixation and Slow Eye Movements", 1986-88. (Role: H.Wyatt & J. Pola Co-Investigators)
NSF Grant BNS-84-6403, "Control of Smooth Pursuit Eye Movementsin the Alert Monkey" (Doctoral Dissertation Research), 1984-86. (Role: J. Pola, C. Neary & H. Wyatt Co-Investigators)
NIH/NEI Grant EY-02878, "The Mechanism of Smooth Pursuit Eye Movements", 1979-84. (Role: J. Pola & H. Wyatt Co-Investigators)
Optometric Center of New York Foundation, "Analysis of the Pupillary Light Reflex", 1978-79. (Role: P.I.)

 

 

Patents

 

"Apparatus and Method for Assessing Retinal Damage" (Domestic Patent granted; International Patents applied for; technology licensed.)
"A Method for Improving the Accuracy of Video-Based Eyetrackers"
"A Method For Reducing Test-Retest Variability In Tests Of Visual Fields"
(Provisional Patent applications)

 

 

Publications

 

Wyatt H.J. (2011) Automated perimetry: using gaze-direction data to improve the estimate of scotoma edges. Investigative Ophthalmology & Visual Science 52: 5818–5823.
Wyatt H.J. (2010) The human pupil and the use of video-based eyetrackers. Vision Research 50: 1982–1988
Shyu, B. and Wyatt H.J. (2009) The appearance of the human eye: optical contributions to the "limbal ring". Optometry and Vision Science 86: E1069-E1077.
Chen Y., Wyatt H.J., Swanson W.H and Dul M.W. (2008) Rapid pupil-based assessment of glaucomatous damage. Optometry and Vision Science 85: 471-481.
Wyatt H.J., Dul M.W. and Swanson W.H. (2007) Variability of visual field measurements is correlated with the gradient of visual sensitivity. Vision Research. 47: 925-936. http://www.pubmedcentral.gov/articlerender.fcgi?artid=2094527
Chen Y., Wyatt H.J. and Swanson W.H. (2005) Pupillary evaluation of retinal asymmetry: development and initial testing of a technique. Vision Research 45: 2549-2563. http://www.pubmedcentral.gov/articlerender.fcgi?artid=1633710
Chepaitis A., Griffiths F., Wyatt H.J. and O'Connell W.F. (2004) Evaluation of tactile fonts for use by a visually impaired elderly population. Visual Impairment Research 6: 111-134.
Chen Y. and Wyatt H.J. (2004) Effects of changing the direction of gravity on sector pupil dilations. Optometry and Vision Science 81: 629-635.
Wyatt H.J. (2004) Modelling transport in the anterior segment of the eye. Optometry and Vision Science 81: 272-282. [Erratum: Optometry and Vision Science 81: 478.]
Wyatt H.J. and Lustgarten M. (2001) Probing anterior segment kinetics with focally applied mydriatics.Journal of Ocular Pharmacology & Therapeutics 17: 461-473.
Pola J. and Wyatt H.J. (2001) Offset dynamics of human smooth pursuit eye movements: effects of varying feedback following target jump ahead of the fovea. Vision Research 41: 655-669.
 Wyatt H.J., Hall E.C. and Engber K. (2000) Representation of simple graphs in virtual tactile space. Journal of Visual Impairment & Blindness 94: 713-716.
Wyatt H.J. (2000) A minimum-wear-and-tear  meshwork for the iris. Vision Research 40: 2167-2176.
Wyatt H.J. (1998) Detecting saccades with jerk. Vision Research38:2147-2153.
Pola J. and Wyatt H.J. (1997) Offset dynamics of human smooth pursuit eye movements: effects of target presence and subject intention. Vision Research 37:2579-2595.
Aquilante K., Wyatt H. and Yager D. (1997) Eye movements of congenital nystagmats are slower during RSVP reading than during PAGE reading. In: Non-invasive Assessment of the Visual system (Yager D., ed) Optical Society of America, Trends in Optics and Photonics, 11: 127-131.
Wyatt H.J. (1996) Ocular pharmacokinetics and convectional flow: evidence from spatio-temporal analysis of mydriasis. Journal of Ocular Pharmacology & Therapeutics 12: 441-459.
Wyatt H.J. and Fisher R.F. (1995) A simple view of age-related changes in the shape of the lens of the human eye. Eye 9: 772-775.
Wyatt H.J., Pola J., Lustgarten M. and Aksionoff E. (1995) OKN suppression by fixation of a stabilized target: the effect of OKN-stimulus predictability. Vision Research 35: 2903-2910.
Wyatt H.J. (1995) The form of the human pupil. Vision Research 35: 2021-2036.
Pola J., Wyatt H.J. and Lustgarten M. (1995) Visual fixation of a target and suppression of OKN: effects of varying target feedback. Vision Research 35: 1079-1087.
Pola J. and Wyatt H.J. (1994) Smooth pursuit eye movement: target velocity starts it; target position stops it. In: Contemporary Ocular Motor and Vestibular Research: A Tribute to David A. Robinson (Fuchs A.F., Brandt T., Büttner U. and Zee D., eds.). George Thieme Verlag, Stuttgart (pp. 142-148).
Wyatt H.J., Pola J., Fortune B. and Posner M. (1994) Smooth pursuit eye movements with imaginary targets defined by extrafoveal cues. Vision Research 34: 803-820.
Pola J. and Wyatt H.J. (1993) Role of Attention and Cognitive Processes. In: Visual Motion and its Role in the Stabilization of Gaze (Wallman J. and Miles F.A., eds.). (Reviews of Oculomotor Research, Vol. 5), Elsevier (pp 371-392).
Wyatt H.J. (1993) Application of a simple mechanical model of accommodation to the aging eye. Vision Research 33: 731-738.
Pola J., Wyatt H.J. and Lustgarten M. (1992) Suppression of optokinesis by a stabilized target: effects of instruction and stimulus frequency. Perception and Psychophysics 52: 186-200.
Wyatt H.J. (1992) A hypothesis concerning retinotopy in the optic nerve head and its relationship to perimetry. Clinical Vision Sciences 7:53-61.
Wyatt H.J. (1991) Modelling the kinetics of topically-applied ophthalmic agents. Optometry and Vision Science 68: 663-665.
Pola J. and Wyatt H.J. (1991) The smooth pursuit eye movement system: response characteristics, stimuli, and mechanisms. In: Vision and Visual Dysfunction; Volume 8: Eye Movements (Carpenter R.H.S., ed), MacMillan, London (pp 138-156).
Ettinger E.R., Wyatt H.J. and London R. (1991) Anisocoria: variation and clinical observation with different conditions of illumination and accommodation. Investigative Ophthalmology & Visual Science 32: 501-509.
Wyatt H.J., Pola J. and Lustgarten M. (1989) The oculomotor "twitch" - a transient response to target motion. Experimental Brain Research 76: 581-592.
Pola J. and Wyatt H.J. (1989) The perception of target motion during smooth pursuit eye movements in the open-loop condition: the characteristics of retinal and extraretinal signals. Vision Research 29: 471-483.
Wyatt H.J. and Pola J. (1988) Predictive behavior of optokinetic eye movements. Experimental Brain Research 73: 615-626.
Wyatt H.J., Pola J. and Lustgarten M. (1988) "Passive suppression" of optokinesis by stabilized targets. Vision Research 28: 1023-1029.
Wyatt H.J. (1988) Manual of Visual Anatomy and Physiology, New York, Fairchild.
Wyatt H.J. (1988) Some aspects of the mechanics of accommodation. Vision Research 28: 75-86.
Wyatt H. J. and Pola J. (1987) Smooth eye movements with step-ramp stimuli: the influence of attention and stimulus extent. Vision Research 27:1565-1580.
Neary C., Pola J. and Wyatt H.J. (1986) Target position: a stimulus for smooth pursuit eye movements in the monkey. In: Eye Movements from Physiology to Cognition, Edited Proceedings of the Third European Conference on Eye Movements (Dourdan, France, 1985); Eds. O'Regan J.K. and Levy-Schoen A., Elsevier North Holland, Amsterdam.
Pola J. and Wyatt H.J. (1985) Active and passive smooth eye movements: effects of stimulus size and location. Vision Research 25: 1063-1076.
Wyatt H.J. and Pola J. (1984) A mechanism for suppression of optokinesis. Vision Research 24: 1931-1945.
Wyatt H.J. and Pola J. (1983) Smooth pursuit eye movements under open-loop and closed-loop conditions. Vision Research 23: 1121-1131.
Wyatt H.J. and Musselman J.F. (l98l) Pupillary light reflex in humans: evidence for an unbalanced pathway from nasal retina, and for signal cancellation in brainstem. Vision Research 21: 5l3-535.
Wyatt H.J. and Pola J. (l98l) Slow eye movements to eccentric targets. Investigative Ophthalmology & Visual Science 21: 477-483.
Pola J. and Wyatt H.J. (l980) Target position and velocity: the stimuli for smooth pursuit eye movements. Vision Research 20: 523-534.
Wyatt H.J. and Pola J. (l979) The role of perceived motion in smooth pursuit eye movements. Vision Research 19: 6l3-6l8.
Wyatt H.J. (l978) Naso-temporal overlap and visual field sparing. Investigative Ophthalmology & Visual Science 17: ll28-ll30.
Wyatt H.J. (l978) Purkinje's methods for visualizing the internal retinal circulation: a look at the source. Vision Research 18: 875-877.
Caldwell J., Daw N.W. and Wyatt H.J. (l978) Effects of picrotoxin and strychnine on rabbit retinal ganglion cells: lateral interaction for cells with more complex receptive fields. Journal of Physiology 276: 277-298.
Daw N.W. and Wyatt H.J. (l976) Kittens reared in a unidirectional environment: evidence for a critical period. Journal of Physiology 257: l55-l70.
Wyatt H.J. and Daw N.W. (l976) Specific effects of neurotransmitter antagonists on ganglion cells in rabbit retina. Science 191: 204-205.
Wyatt H.J. with Ellis R.A. (l975) A special-purpose computer system for on-line generation and display of "random-dot" stimuli for stereoscopic vision experiments. In: Proceedings of the Second Annual Conference on Computer Graphics and Interactive Techniques, June 25-27, l975, Bowling Green, Ohio. (Publ. Assoc. for Computing Machinery.) pp.lll-ll4.
Wyatt H.J. and Daw N.W. (l975) Directionally sensitive ganglion cells in the rabbit retina: specificity for stimulus direction, size and speed. Journal of Neurophysiology 38: 6l3-626.
Daw N.W. and Wyatt H.J. (l974) Raising rabbits in a moving visual environment: an attempt to modify directional sensitivity in the retina. Journal of Physiology 240: 309-330.
Wyatt H.J. (l974) Singly and doubly contingent after-effects involving color, orientation and spatial frequency. Vision Research 14: ll85-ll93.
Wyatt H.J. (l972) Scotopic vision: an unexpected threshold elevation produced by dark stimuli. Vision Research 12: 2l47-2l50.
Wyatt H.J. (l97l) Spatial interactions in adaptation of human scotopic vision. Ph.D. Thesis, University of California, Berkeley.
 

Invited Review

 

(1994) Physiology of the the Eye -  an Introduction to the Vegetative Functions. (2nd ed) Fatt I and Weissman B.A. Reviewed in: Optometric Education 19:63.

Recent Presentations

 

"Retest Variability and the Gradient of the Visual Field: Blind Spot vs. Scotoma."  H.J. Wyatt, J.Chan, W.H. Swanson, & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 27-May 1, 2008 (abstract accepted).
"Retinal asymmetry in patients with glaucoma: comparison of pupillary light reflex and nerve fiber layer thickness." H.J. Wyatt, H. McLeod, R. Madonna, M.W. Dul & W.H. Swanson. A.A.O. Fall Meeting, Tampa, Florida, Oct. 24-27, 2007.
"Report on a pupil-based approach to glaucoma testing." H.J. Wyatt, W.H. Swanson, M. Dul & Y. Chen. North American Perimetry Society, Skaeateles, NY, Sept 26-27, 2007.
"Retest variability is correlated with gradient of the visual field near the normal physiological blind spot." H.J. Wyatt, J. Lam, J. Chan, W.H. Swanson & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 5-9, 2007.
"Retest variability is correlated with gradient of the visual field near the normal physiological blind spot." H.J. Wyatt, J. Lam, J. Chan, W.H. Swanson & M.W. Dul. A.A.O. Fall Meeting, Denver, Colorado, Dec 8, 2006.
"Variability of visual field measurements is correlated with the gradient of sensitivity." H.J. Wyatt and M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May4, 2006.
"Variability of visual field measurements is correlated with the gradient of sensitivity." H.J. Wyatt and M.W. Dul. North American Perimetry Society, Skaeateles, NY, Sept 22-23, 2005.
AA rapid test to evaluate upper/lower retinal asymmetry in glaucomatous optic neuropathy using the pupil light reflex.@ Y.Chen, H.J. Wyatt, W.H. Swanson & M.W. Dul. 26th Pupil Colloquium, Bear Mountain, NY, Aug22-26, 2005.
"Use of response amplitude to complement response balance in a pupil based system for assessing glaucomatous damage." H.J. Wyatt, Y. Chen, W.H. Swanson & M.W. Dul. 26th Pupil Colloquium, Bear Mountain, NY, Aug22-26, 2005.
"Rapid assessment of glaucomatous damage with the pupillary light reflex: asymmetry and amplitude measures of abnormality" Y. Chen, H.J. Wyatt, W.H. Swanson & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 1-5, 2005.
"Comparison of the elia and braille tactile alphabets for adult visually impaired readers" A.J. Chepaitis, A.Griffiths, H.J. Wyatt & K.Aquilante. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 1-5, 2005.
"A new pupil-based approach to glaucoma testing: design and initial studies" H.J. Wyatt, Y. Chen, W.H. Swanson & M.W. Dul. A.A.O. Fall Meeting, Tampa, Florida, Dec 9-12, 2004.
"A new pupil-based approach to glaucoma testing: application of the method to glaucoma patients" Y.Chen, H.J. Wyatt, W.H. Swanson & M.Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004.
"A new pupil-based approach to glaucoma testing: design and initial testing" H.J. Wyatt, Y.Chen & W.H. Swanson. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004.
"Reading with simulated rp: effects of visual field size" K.Ma, H.Wyatt, D.Yager & D.D. Lin. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004. "A new approach to assessing glaucomatous damage using pupillometry." H.J. Wyatt, Y. Chen & W.H. Swanson. 25th Pupil Colloquium, Crete, Greece, September 10-14, 2003.
"Testing the ability of seniors to learn and read tactile alphabets." A.J. Chepaitis, A.F. Griffiths, H.J. Wyatt & W.F. O'Connell. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 4-9, 2003.
"Modeling anterior segment kinetics" H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 5-10, 2002.
"Anterior segment pharmacokinetics: how things move around" H.J. Wyatt, The 24th Pupil Colloquium, Asilomar, California, September 7-11, 2001.
"Modeling the mydriatic pathway to the pupil." H.J. Wyatt & Y. Chen, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 29-May 4, 2001.
"Nonlinear iris stretch and an iris 'minimum-wear-and-tear' meshwork." H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.
"Normal subjects reading rsvp text slowly make saccades." K. Aquilante, H.J. Wyatt, D. Yager & R.A. Morris, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.
"Using sector pupil dilation and head tilt to map anterior segment kinetics and convectional flow." Y. Chen & H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.