1972: Ph.D. (Biophysics) New York University, New York, NY
Present Positions:
2005 - present |
Distinguished Teaching Professor of Biological Sciences, Course Director, General Pharmacology, SUNY, College of Optometry, New York, NY 10036 |
2004 - present |
Adjunct Professor of Ophthalmology, Columbia University, New York |
2007 |
Visiting Professor of Ophthalmology, Xiamen University, Xiamen, Peoples Republic of China |
1998 - Present |
Visiting Professor of Physiology and Cell Biology (in Ophthalmology) Columbia University, College of Physicians and Surgeons, New York , NY 10032 |
1997 - Present |
Professor of Biological Sciences, |
2002 - present |
Visiting Professor of Molecular Biology, Shanghai Second Medical School, Shanghai, China |
1997 - present |
Professor of Biological Sciences, Course Director, General Pharmacology, SUNY, College of Optometry, New York, NY 10036 |
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Previous Positions Held:
1997 - 2004 |
Professor of Biological Sciences, Course Director, General Pharmacology, 1997 - 2004 |
1994 - 1997 |
Associate Professor of Biological Sciences, |
1989 - 1994 |
Associate Professor of Physiology and Endocrinology |
1982 - 1989 |
Assistant Professor of Ophthalmology |
1980 - 1982 |
Assistant Professor of Ophthalmology |
1976 - 1982 |
Research Assistant Professor of Ophthalmology |
1972 - 1976 |
Fellow in Ophthalmology (recipient of individual NEI fellowship and research grant) |
1994 – 1997 |
Associate Professor of Biological Sciences, Course Director, General Pharmacology, SUNY College of Optometry, New York, NY 10036 |
1989 – 1994 |
Associate Professor of Physiology and Endocrinology, Medical College of Georgia, Augusta, Georgia 30912 |
1982 – 1989 |
Assistant Professor of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri 63110 |
1980 - 1982 |
Assistant Professor of Ophthalmology, Mount Sinai School of Medicine, New York, NY 10029 |
1976 –1982 |
Research Assistant Professor of Ophthalmology, Mount Sinai School of Medicine, New York, NY 10029 |
1972 - 1976 |
Fellow in Ophthalmology (recipient of individual NEI fellowship and research grant), Mount Sinai School of Medicine, New York, NY 10029 |
Committee Services:
Chairman of Physiology and Pharmacology
Program Planning Committee: Association for Research in Vision and Ophthalmology
Basic Research Science Review Committee
Faculty Tenure and Promotion Committee
Member of AIBS Review Board for evaluation of refractive surgical safety
Regular member Study Section AED CSRA February 2005
Scientific consultant for Wakamoto Pharmaceuticals December 2004
Regular member Visual Sciences Study Section, AED, National Eye Institute, Center
Scientific Review 1997 - 2002
Regular Member of Small Business Review Committee SBRN-4 (NIH)1999 - present
American Institute of Biological Science Special Study Section Member: Refractive Surgery Evaluation for Military 1998 - present
Member of Editorial Board: Proceedings of the Society of Experimental Biology and Medicine 1998 - present
Ad. Hoc. member Visual Sciences Study Section, VISC, National Eye Institute 1996 - 1997
Ad. Hoc. member Visual Sciences Study Section, VISA, National Eye Institute 1996 - 1997 and 2003
Member of Scientific Advisory Board, Santen Pharmaceutical, Osaka, Japan (Scientific Advisor and Manuscript Support for journal submission) 1992-present
Scientific Consultant, Wakamoto Pharmaceutical Co. Tokyo, Japan (Scientific Advisor, support for product presentation to overseas pharmaceutical companies and Manuscript Support for journal submission) 2002-present
Graduate Student Committee
Graduate Student Admissions: Wei Dai (New York Medical College); Sylvia Kang, Fan Zhang, José Capó-Aponte , Zan Pan (SUNY, State College of Optometry)
Doctoral Students: Thesis Committee Member
Wei Dai (New York Medical College); John Sullivan (Mount Sinai School of Medicine)
Masters Students: Thesis Supervisor
Cindy Wang; Fan Zhang; Jojo Du; Wenhong Tao; Weiching Wu; Sylvia Kang; Viviana Tores; José Capó-Aponte;Zan Pan
Laboratory Rotations
Mark Klepner; Don Williams; José Cruz
Professional and Scholarly Associations:
American Physiological Society - Present
Association for Research in Vision and Ophthalmology (ARVO) - Present
Editorial Services (Reviewer):
Current Eye Research
Investigative Ophthalmology and Visual Sciences
American Journal of Physiology
Biochimica et Biophysica Acta
National Science Foundation
Journal of Membrane Biology
Experimental Eye Research
Burroughs Wellcome Trust
Hong Kong Research Foundation
Physiological Genomics
Ophthalmic Research
Experimental Biology and Medicine
Chancellors Award from SUNY for Outstanding Scientific Achievement 2003
Fight for Sight Research Award for Scholarly Excellence 1985
$90,000 (per year)/3 years Academic Investigator Award, National Eye Institute 1977
New York University, Distinguished Ph.D. Dissertation Award 1972
PHARMACEUTICAL COMPANY CONTRACTS:
Resolvyx Pharmaceuticals: Beverly, MA: Roles of Resolvins in Reducing Ocular Inflammation. $50,000 per year
RESEARCH GRANT AND FELLOWSHIPS (PRIMARY INVESTIGATOR):
Monbusho International Research Fellow
Ministry of Education, Japan (1991)
Title: Control of Corneal Epithelial Proliferation
Amount: $300,000 /year
Source:National Eye Institute
Duration: 2003-2008
Status: Active
Title: Control of Corneal Epithelial Proliferation
Amount: $180,000/year
Source:National Eye Institute
Duration:1998 - 2003
Status: Completed
Title: Control of Corneal Epithelial Proliferation
Amount: $125,000/year
Source:National Eye Institute
Duration:1993 - 1998
Status: Completed
Title: Roles of regulatory volume behavior in maintenance of ocular health
Amount: $20,000/year
Source:Georgia Research Supplemental Support
Duration:1992 - 1994
Status:Completed
Title: Second Messenger Roles of cAMP and Ca2+ in Corneal Epithelium
Amount: $142,000/year
Source:National Eye Institute
Duration:1986 - 1991
Status: Completed
Title: Supplement for Impedance Analysis
Amount: $27,500
Source:National Eye Institute
Duration:1984
Status: Completed
Title: Coupling Between Metabolism and Active Ion Transport/Cornea
Amount: $120,000/year
Source:National Eye Institute
Duration:1983 - 1986
Status: Completed
Title: Basic Research Science Grant
Amount: $10,000
Source: Washington University
Duration: 1983
Status: Completed
Title: DC Microelectrode Studies (Supplement)
Amount: $13,211
Source:National Eye Institute
Duration:1982
Status: Completed
Title: Coupling Between Metabolism/Active Ion Transport/Cornea
Amount: $105,000/year
Source:National Eye Institute
Duration: 1980 - 1983
Status: Completed
Title: “Coupling Between Metabolism/Active Ion Transport in Cornea”
Amount:$90,000/year
Source:National Institutes of Health
Duration1977 - 1980
Status: Completed
Title: Effects of Diuretics on Corneal Hydration and Transport
Amount: $75,000/year
Source:National Eye Institute
Duration:1976
Status: Completed
Individual NEI Postdoctoral Fellowship, ($10,000/year) 1973 - 1976
Research Grant Submitted: R21 to NEI (Oct 1, 2005: Signaling mechanisms mediating mouse corneal epithelial healing; 275,000/2 years)
LECTURES AND PRESENTATIONS: (Titles are listed for presentationsin recent years)
- XVII International Congress of Eye Research (ICER), Buenos Aires, Argentina (Dec 2006); Transient receptor potential vanilloid 1 activation in corneal epithelial cells mediates a pro-inflammatory response.
- University of Miami (June 2005); EGF mediated signaling in corneal epithelial cells.
- New York Medical College (March 2005); TRP expression is required for the mitogenic response to EGF.
- Kyoto University (December 2004); Dependence of corneal epithelial proliferation on PKC isoform expression.
- Indiana University (March 2004); How does EGF mediate control of corneal epithelial cell migration?
Reinach, P.S., Capó-Aponte, J.E., Mergler, S., Pokorny, K.S. Roles of corneal epithelial transport mechanisms in mediating responses to cytokines and osmotic stress, in Ocular Transporters: In Ophthalmic Diseases and Drug Delivery, eds. Tombran-Tink, J. and Barnstable, C.J., Humana Press, Totowa, NJ, in press (2007).
PUBLICATIONS-Peer Reviewed Journals
1.Reinach, P.S. and Brody, S.S. (1972). Titration of monomolecular films of bacteriochlorophyll and cytochrome c at an air-water interface. Biochemistry 11:92-100.
2.Reinach, P.S. and Brody, S.S. (1973). Surface and spectral properties of bacteriochlorophyll and its derivatives in monomolecular films at an air-water interface. Biochimica. Biophysica. Acta. 314:360-371.
3.Reinach, P.S., Candia, O.A. and Siegel, G. (1975). Lithium transport and (Na+K) ATPase in the isolated frog skin epithelium. J. Membrane Biol. 25:75-92.
4.Candia, O.A. and Reinach, P.S. (1977). Sodium washout kinetics across outer and inner barriers of the isolated frog skin epithelium. Biochimica Biophysica. Acta. 468:341-352.
5.Reinach, P.S., Schoen, H. and Candia, O.A. (1977). Effects of inhibitors of Na and Cl transport in the bullfrog cornea on oxygen uptake. Exp.Eye Res. 24:493-500.
6.Guerschanik, S., Reinach, P.S. and Candia, O.A. (1977). Chloride compartments of the frog lens and chloride permeabilities of its isolated surfaces. Invest. Ophthalmol. 16:515-520.
7.Reinach, P.S. and Candia, O.A. (1978). Effects of tryptamine on active transepithelial Na and Cl transport in isolated bullfrog cornea. Biochimica. et Biophysica. Acta 510:327-338.
8.Erlij, D., Sliva, P. and Reinach, P.S. (1978). Effects of adenosine on fluid output and Cl secretion in the isolated rectal gland. Mount Desert Island Biological Bulletin. 18:21-25.
9.Reinach, P.S., Schoen, H.F. and Candia, O.A. (1979). Metabolic requirements of anaerobic active Cl and Na transport in the isolated bullfrog cornea. Am. J. Physiol. 236 (5): C268-276.
10.Reinach, P.S., Schoen, H.F. and Candia, O.A. (1979). Energetic requirements of active transepithelial Na and Cl transport in the isolated bullfrog cornea. Exp. Eye Res. 29:637-646.
11.Sun, A.S., Alvarez, L., Reinach, P.S. and Rubin, E., (1979). Absence of 5'-Nucleotidase activity in virus transformed fibroblast cells. Laboratory Invest. 41(1):1-5.
12.Lanzetta, P., Alvarez, L., Reinach, P.S. and Candia, O.A. (1979). An improved assay for nanomole amounts of inorganic phosphate. Analytical Biochemistry. 100:95-97.
13.Nagel, W. and Reinach, P.S. (1980). Mechanism of stimulation by epinephrine of active Cl transport in the isolated frog cornea. J. Membrane Biol. 56:73-79.
14.Erlij, D., Shen, W.K., Reinach, P. and Schoen, H. (1982). The effect of excitation-contraction uncouplers on the K+-stimulated respiration of frog skeletal muscle. Am. J. Physiol. 243:C87-95.
15.Candia, O.A. and Reinach, P.S. (1982). Thermodynamic analysis of active sodium and potassium transport in frog corneal epithelium. Am. J. Physiol. 242:F690-F698.
16.Reinach, P.S. and Pasnikowski, E. (1983). Phosphorylated metabolites and effects of amphotericin B and ouabain on phosphorylation state in amphibian cornea. Exp. Eye Res.36:633-644.
17.Eggena, P. and Reinach, P. (1982). Vasopressin‑resistance induced by low sodium and high mannitol in toad bladder. Endocrin. 111(3):1001-1009.
18.Reuss, L., Reinach, P.S., Weinman, S. and Grady, T. (1983). Intracellular ion activities and chloride transport mechanisms in bullfrog corneal epithelium. Am. J. Physiol. 244:C336-C347.
19.Candia, O.A., Reinach, P. and Alvarez, L. (1984). Active potassium transport in frog corneal epithelium Na:K coupling flux ratio. Am. J. Physiol. 247:C454-C461.
20.Reinach, P. and Kirchberger, M. (1983). Evidence for catecholamine‑stimulated adenylate cyclase activity in frog and rabbit corneal epithelium and cyclic AMP dependent protein kinase and its protein substrates in frog corneal epithelium. Exp. Eye Res. 37:326-335.
21.Patarca, R., Candia, O.A. and Reinach, P.S. (1983). Mode of inhibition of active Cl transport in the frog cornea by furosemide. Am. J.Physiol. 245:F660-F669.
22.Krupin, T., Reinach, P., Candia, O.A., Podos, S.M. (1984). Transepithelial electrical measurements on the isolated rabbit iris-cililary body. Exp. Eye Res. 38:114-123.
23.Huff, J.W. and Reinach, P. (1985). Mechanism of inhibition of net ion transport across frog corneal epithelium by calcium channel antagonists. J. Membrane Biol. 85(3):215-224.
24.Reinach, P. and Nagel, W. (1985). Implications of an anomalous intracellular electrical parameter response in frog corneal epithelium. J. Membrane Biol. 87:201-209.
25.Reinach, P. (1985). Role of cyclic AMP and Ca2+ in epithelial ion tranport across corneal epithelium: Review Curr. Eye Res. 4(4):385-391.
26.Clausen, C., Reinach, P. and Marcus, D. (1986). Membrane transport parameters in frog corneal epithelium measured using impedance analysis techniques. J. Membrane Biol. 91:213-225.
27.Goligorsky, M., Reinach, P., Westbrook, S. and Hruska, K. (1986). Demonstration of a direct effect of atrial natriuretic factor on cultured pig kidney cells. Mineral and Metabolism 13:51-56.
28.Reinach, P. and Holmberg, N. (1987). Ca-stimulated Mg dependent ATPase activity in a plasma membrane enriched fraction of bovine corneal epithelium. Curr. Eye Res. 6:399-405.
29.Reinach, P., Thurman, C. and Klemperer, G. (1987). Basolateral membrane K+ permselectivity and regulation in bullfrog cornea epithelium. J. Membrane Biol. 99:205-213.
30.Cork, R.J., Reinach, P., Moses, J. and Robinson, K.R. (1987). Ca does not act as a second messenger for adrenergic and cholinergic agonists in corneal epithelial cells. Curr. Eye Res. 6:1309-1317.
31.Reinach, P. and Holmberg, N. (1989). Inhibition by calcium of beta adrenoceptor mediated cAMP responses in isolated bovine corneal epithelial cells. Curr. Eye Res. 8:85-90.
32.Tarvin, J.T., Reinach, P.S. and Jackson, D.L. (1988). Measurement and analysis of impedance in epithelial membranes. In: Biological and Synthetic Membranes. 389-399, A. Liss, New York, N.Y.
33.Reinach, P., Thurman, C., Bazan, H.E.P. and Bazan, N.G. (1989). Reversal of the epinephrine stimulation of Cl transport in bullfrog cornea. Exp. Eye Res. 49:739-749.
34.Reinach, P. and Schoen, H.F. (1990). NPPB inhibits a basolateral membrane K+ conductance in the isolated frog corneal epithelium. Biochimica. et. Biophysica. Acta. 1026:13-20.
35.Reinach, P., Holmberg, N., and Chiesa, R. (1991). Identification of a calmodulin sensitive Ca2+ transporting ATPase in the plasma membrane of bovine corneal epithelial cells. Biochimica et Biophysica Acta 1068:1-8.
36.Reinach, P., Tarvin, J.T., and Hirsch, M. (1991). Changes in cellular membrane and paracellular conductances by amphotericin B in the epithelium of the bullfrog cornea. Biochimica et Biophysica Acta 1066:115-123.
37.Chu, T.C., Reinach, P. and Green, K. (1990). Direct stimulation by succinate of Na:K pump in rabbit ciliary epithelium. Curr. Eye Res. 9(8):787-792.
38.Steinsapir, J., Socci, R. and Reinach, P. (1991). Effects of androgen on intracellular calcium of LNCaP cells. Biochem. and Biophys. Res. Comm. 179(1):90-96.
39.Walkenbach, R.J., Guo-Sui Ye, Reinach, P.S and Boney, F. (1991). Alpha1-adrenoceptors in human corneal epithelium. Invest. Ophthal. 32:3067-3072.
40.Reinach, P.S., Socci, R., Keith, C. and Scanlon, M. (1992). Adrenergic receptor mediated increase of intracellular Ca2+ concentration in isolated bovine corneal epithelial cells. Comp. Biochem. Physiol. 102A:709-714.
41.Zamorano, V., Ganapathy, V., Sharawy, M. and Reinach, P. (1992). Evidence for an ATP-driven H+ pump in the plasma membrane of the bovine corneal epithelium. Exp. Eye Res. 55:269-277.
42.Walkenbach, R.J., Guo-Sui Ye, Reinach, P.S. and Boney, F. (1992). Alpha1-adrenoceptors in the corneal endothelium. Exp. Eye Res. 55:443-450.
43.Torres-Zamorano, V., Ganapathy, V. and Reinach, P. (1993). Characterization and subtype identification of Na-H exchanger in bovine corneal epithelium. Curr. Eye Res. 12:69-76.
44.Reinach, P., and Tarvin, J.T. (1993). Independence of Na:K pump activity and basolateral membrane conductance in bullfrog corneal epithelium. Comp. Biochem. and Physiol. 106A:455-461.
45.Takagi, H., Reinach, P., Tachado, S. and Yoshimura, N. (1994). Endothelin mediated cell signaling and proliferation in cultured rabbit corneal epithelial cells. Invest. Ophthal. Vis. Sci. 35:134-142.
46.Socci, R., Chu, A., Reinach, P. and Meszaros, L. (1993). Ca2+ - induced Ca2+ release from a ryanodine-sensitive intracellular Ca2+ store in corneal epithelial cells. Comp. Biochem. And Physiol. 106B:793-797.
47.Reinach, P., Ganapathy, V. and Torres-Zamorano, V. (1994). H exchanger subtype mediates volume regulation in bovine corneal epithelial cells. Adv. In Exp. Biol. And Medicine 350:105-110.
48.Takagi, H., Reinach, P., Yoshimura, N. and Honda, Y. (1994). Endothelin-1 promotes wound healing in rabbit corneal epithelium. Curr. Eye Res. 13: 625-628.
49. Nakamura, K., Riva, C., Reinach, P., Mita, S. (1996). Effects of endothelin- on optic nerve head blood flow in cats. J. Ocular Pharma. 12:75-83.
50. Tao, W., Wu, X. and Reinach, P.S. (1995). ETB and EGF receptor stimulation of wound closure in bovine corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 36”2614-2622.
51. Socci, R., Tachado, S., Aronstam, R.S. Reinach, P.S. (1996). Characterization of muscarinic receptor subtypes in the bovine corneal epithelial cells. J. Ocular Pharm and Therapeutics 12: 259-171.
52.Takashima, Y., Takagi, H., T. Takahashi, M., Reinach, P., Mircheff, A., Warren, D. W. and Yoshimura, N. (1996). Endothelin protein expression in tear glands of the rabbit. Current Eye Res. 15(7): 768-773.
53.Tao, W., WU, X., Liou, G., Abney, T. and Reinach, P. (1997). Endothelin receptor mediated Ca2+. Signaling and isoform expression in cultured bovine corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 38: 130-141.
54.Wu, X., Yang, H., Fischbarg, J. and Reinach, P. (1997). Involvement of ryanodine sensitive Ca2+ release in regulatory volume decrease by cultured rabbit corneal epithelial cells. J. Membrane Biology 158:127-136.
55.Wu, X. Torres-Zamorano, V. and Reinach, P.S. (1998). ETA receptor mediated inhibition of pH regulation in cultured bovine corneal epithelial cells. Exp. Eye Res. 66:699-708.
56.Bildin, V.N., Yang, H., Fischbarg, J. and Reinach, P.S. (1998). Effects of chronic hypertonic stress on regulatory volume increase and Na:K:2Cl cotransporter expression in cultured corneal epithelial cells. Adv. in Exp. Biol. and Med. 438:637-642
57.Iserovich, P. Reinach, P. Yang, H., and Fischbarg, J. (1998). A novel approach to resolve cellular volume responses to an anisotonic challenge. Adv. in Exp. Biol. and Med. 438:687-692.
58.Hara, E., Reinach, P.S., Iserovich, P. and Fischbarg, J. (1999). Effects of prozac on regulatory volume responses and K+ fluxes in cultured bovine corneal endothelial cells. J. Membrane Biol. 171:75-85.
59.Harino, S., Nishimura, K., Kitanishi, K. Suzuki, M., and Reinach, P.S. (1999). Role of NO in autoregulation of blood flow to decreased perfusion pressure in the cat retina. J. Ocular Pharmacol. 15:295-303.
60.Yang, H. Reinach, P.S., Koniarek, J.P., Wang, Z., Iserovich, P. and Fischbarg, J. (2000). Fluid transport by cultured corneal epithelial cell layers. British. J. Ophthalmology 84:199-204
61.Kang, S.K., Xu, D., Reinach, P.S., Luo, L. (2000). Inhibitory effect of PGE2 on EGF-induced MAP kinase activity and rabbit corneal epithelial proliferation. Invest. Ophthalmol. Vis. Sci. 41:2164-2170.
62.Bildin, V.N., Yang, H., Crook, R.B., Fischbarg, J. and Reinach, P.S. (2000). Differential hypertonic-induced increases in proliferation, Na:K:2Cl cotransport functional activity, protein and gene expression in SV40-transformed rabbit and human corneal epithelial cells. J. Membrane Biology 177:41-50.
63.Reinach P.S., Li, T., Lu, L.( 2000). Okadaic acid suppresses TPA-induced differentiation by stimulating G1/S transition in human myeloblastic leukaemia ML-1 cells. Cell Prolif. 33(4):189-202.
64.Kuang, K., Li, Y., Wen, Q., Wang, Z., Li, J., Yang, Y., Iserovich, P., Reinach, P.S., Sparrow, J., Diecke, F.P., Fischbarg, J. ( 2001). Corneal endothelial NKCC: molecular identification, location, and contribution to fluid transport. Am. J. Physiol. Cell Physiol. 280(3):C491-C499.
65.Luo, L., Reinach, P.S., and Kao, W.-Y. (2001). Cytokine mediated control of corneal wound healing:minireview. Exp. Biol. and Med. 226: 653-664.
66.Al-Nakkash, L., Reinach, P.S. 2001. Activation of a CFTR-mediated chloride current in a rabbit corneal epithelial cell line. Invest. Ophthal. Vis. Sci. 42: 2364-2370.
67.Yang, H., Wang, Z., Miyamoto, Y., Reinach, P.S. (2001). Cell signaling pathways mediating epidermal growth factor stimulation of Na:K:2Cl cotransport activity in rabbit corneal epithelial cells. J. Membr. Biol. 183: 93-101.
68.Bildin, V.N., Iserovich, P., Fischbarg, J., Reinach, P.S. (2001). Differential expression of Na:K:2Cl cotransporter, glucose transporter 1 and aquaporin 1 in freshly isolated and cultured bovine corneal tissues. Exp. Biol. Med. 226 919-926.
69.Miyasaka, T., Kaminogawa, S., Shimizu, M., Hisatsune, T., Reinach, P.S., Miyamoto, Y. (2001). Characterization of human taurine transporter expressed in insect cells using a recombinant baculovirus. Protein Expr. Purif. 23: 389-397.
70.Mori, M., Reinach, P.S., Moskowitz, M., Miyamoto, Y. (2002). Hypochlorite suppresses TNFα induced increases in IL-1β expression in human corneal epithelial cells. Invest. Ophthal. Vis. Sci. 43: 3190-3195.
71.Shioda, R., Reinach, P.S., Hisatsune, T., Miyamoto, Y. (2002). Osmosensitive taurine transporter gene and protein expression in human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 43: 2916-2922.
72.Kang, S.S., Wang, L., Kao, W.-Y, Reinach, P.S., Lu, L. (2001). Control of SV40-transformed RCE cell proliferation by growth factor-induced cell cycle progression. Curr. Eye Res. 6:397-405
73.Bildin, V.N., Wang, Z., Iserovich, P., Reinach P.S. (2003). p38 MAPK activation during acute hypertonic stress is required for regulatory volume recovery and maintenance of epithelial layer integrity. J. Membr. Biol. 193: 1-13.
74.Yang, H., Ning, G., Wen, Q., Sun, X., Lu, L., Reinach, P.S. (2003). EGF mediated increases in cell growth requires stimulation of store activated channel activity. J. Membr. Biol. 194 47-58
75.Roderick, C., Wang, L., Reinach, P.S., Lu, L. (2003). Modulation of rabbit corneal epithelial cell proliferation by growth factor-regulated K+ channel activity. J. Membr. Biol. 196: 41-50.
76. Shao, C., Sima, J., Zhang, SX, Jin, J.., Reinach, P., Wang Z, Ma, JX (2004). Suppression of corneal neovascularization by PDGF release from human amniotic membranes. Invest. Ophthalmol. Vis Sci. 45: 1758-1762.
77. Al-Nakkash, L., Iserovich, P. Coca-Prados, M., Yang, H., Reinach, P.S. (2004). Functional and molecular characterization of a volume-activated chloride channel in rabbit corneal epithelial cells. J. Membr. Biol. 201:41-49.
78. Mergler, S., Pleyer, U., Reinach, P., Bednarz, J. Danowski, H., Engelmann, K., Hartmann, C.,Yousif, T. (2005). EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells. Exp. Eye Res. 80:285-293.
79. Wang, L., Reinach, P., Lu, L. (2005). TNFa promotes cell survival through stimulation of K+channel and NFkB activity in corneal epithelial cells. Exp. Cell Res. 311:39-48.
80. Yang, H., Mergler, S., Sun, X., Wang, Z., Lu, L., Bonanno, J.A., Pleyer, U., Reinach, P.S. (2005). TRPC4 knockdown suppresses EGF-induced store operated channel activation and growth in human corneal epithelial cells. J. Biol. Chem. 280: 32230-32237.
81. Capó-Aponte, J., Iserovich, P., Reinach, P.S. (2005). Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells. J. Membrane Biol. 207: 11-22.
82. Zhuang Z.H., Sun, L., Kong, L., Yu, MC, Reinach, P., Zang Z.W., Ge, B.X. (2006). Drosophila TAB2 is required for immune activation of JNK and NF-Kappa B. Cell Signal.964-970.
83. Zhang, F., Wen, Q., Mergler, S. Yang, H., Wang, Z. Bildin, V.N., Reinach, P.S. (2006). PKC isoforms-specific enhancement of capacitative calcium entry in human corneal epithelial cells. Invest. Ophthal. Vis. Sci. 47(9): 3989-4000.
84. Lu, J., Lu, Z., Reinach, P.S., Zhang, J., Dai, W., Lu, L., Xu, M. (2006). TGF-beta2 inhibits AKT activation and FGF-2-induced corneal endothelial cell proliferation. Exp. Cell Res. 312(18): 3631-3640.
85. Kitano, A., Saika, S., Yamanaka, O., Reinach, P.S., Ikeda, K., Okada, Y., Shirai, K., Ohnishi, Y. (2006). Genipin suppression of fibrogenic behaviors of the alpha-TN4 lens epithelial cell line. J. Cataract Refract. Surg. 32(10): 1727-1735.
86. Du, J., Zhang, F. Capó-Aponte, J.E., Tachadao, S.D., Zhang, J., Yu, F.S., Koziel, H., Sack, R., Reinach, P.S. (2006). AsialoGM1 mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5. Invest. Ophthal. Vis. Sci. 47(11): 4810-4818,
87. Wang, Z., Yang, H., Tachado, S.D., Capó-Aponte, J.E., Bildin, V.N., Koziel, H., Reinach, P.S. (2006). Phosphatase-induced MAPK crosstalk mediates control of corneal epithelial cell migration. Invest. Ophthal. Vis. Sci. 47(12):5267-5275.
88. Capó-Aponte, J.E., Wang, Z., Bildin, V.N., Pokorny. K.S., Reinach, P.S. (2006). Fate of hypertonicity-stressed corneal epithelial cells depends on differential MAPK activation and p38MAPK/Na-K-2Cl cotransporter1 interaction. Exp. Eye Res. 84(2):361-372.
89. Capó-Aponte, J.E., Wang, Z., Bildin, V., Iserovich, P., Pan, Z., Zhang, F., Pokorny, K.S., Reinach,P.S. (2007) Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial Cells. Exp. Eye Res. 84: 1090-103.
90. Pan Z, Capo-Aponte, JE., Zhang, F., Wang, Z., Pokorny, K.S.,Reinach, P.S. (2007) Differential dependence of regulatory volume decrease behavior in rabbit corneal epithelial cells on MAPK superfamily activation. Exp Eye Res. 84: 978-90.
91. Zhang, F., Yang, H., Wang, Z., Mergler, S., Kawakita, T., Liu, H., Tachado, S., Pleyer, U., Koziel, H., Kao, W.W., Reinach, P.S. (2007) Transient potential vanilloid1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signaling. J.of Cell Physiol. 213:730-9.
92. Capo-Aponte, JE, Zan, W., Murat Akinci, MA, Wolosin, JM, Pokorny, KS, Iseroivich, P., Reinach, PS (2007)Potassium-Chloride cotransporter mediates cell cycle progression and proliferation of human corneal epithelial cells. Cell Cycle 6 (21) (in press)


