Harry J. Wyatt, Ph.D (Professor Emeritus)

Harry Wyatt
SUNY College of Optometry
33 West 42nd Street
New York, NY 10036

  • Pupil function and the structure of the iris (Iris Model | Sector Dilation Model)
  • Use of the pupillary light reflex to assess retinal status
  • The use of visual information in controlling eye movements
  • Pharmacokinetics and fluid movement in the eye (Movement of a substance applied to the eye)
  • Mechanics of accommodation

  • Ph.D. (Biophysics) 1971, University of California, Berkeley
  • M.A. (Physics) 1967, University of California, Berkeley
  • B.A. (Physics) 1964, Pomona College

  • Department of Biological Sciences, State College of Optometry, State University of New York (SUNY Distinguished Teaching Professor, 1993-2007 (Emeritus, 2007); Chair, 1988-94; Professor, 1984-93; Associate Professor, 1978-84; Assistant Professor, 1975-78)
  • Research Fellow, Department of Physiology & Biophysics, Washington University Medical School, St. Louis, Missouri, 1971-75 (National Institutes of Health Training Grant)
  • Teaching Associate, University of California, Berkeley, 1967-68
  • Teaching Assistant, University of California, Berkeley, 1964-66

  • Invited speaker, Gordon Research Conference on Theoretical Biology and Biomathematics, Tilton, New Hampshire, June 7-11, 1998
  • SUNY Distinguished Teaching Professor, 1993
  • SUNY Chancellor's Award for Excellence in Teaching, 1990

  • NIH/NEI Grant R03EY014549 “A Rapid Pupillometric Test for Glaucoma”, 2003-07. (P.I.)
  • NIH/NEI Grant 5T35EY007079 “Short Term Training Students –Health Professional Schools”, Summer 2005, Summer 2006. (P.I.: K.J. Ciuffreda)
  • Langeloth Foundation Grant “Investigation of Tactile Alphabets and Clinical Protocols to aid in the Rehabilitation of the Visually Impaired” 2004, P.I. Kathy Aquilante (Role: Consultant)
  • Langeloth Foundation Grant “Investigation of a New Tactile Alphabet to Aid in the Rehabilitation of the Adventitiously Blind” 2000, P.I. William O’Connell (Role: Co-Investigator)
  • NIH/NEI Grant 5K23EY000394-05 “S Cone Responses And Neural Pathways For Accomodation”, 1999-2004, P.I.: Frances Rucker (Role: Co-Investigator 2003-2004)
  • NIH/NEI Grant 5K23EY000366-04 “Reading Eye Movements in Nystagmus/Central Field Loss”, 1998-2003, P.I.: Kathy Aquilante (Role: Co-Investigator 1998-2000)
  • NIHNEI Grant 5R01MH047542 “Complex Dynamics And Noise In The Pupil Light Reflex”, 1998-1999, P.I.: John Milton, University of Chicago (Role: Consultant)
  • Schnurmacher Institute for Vision Research, SUNY, “Normal and Abnormal Pupil Function”, 1991-93; “The Mechanical Behavior of the Vitreous”, 1993-94; “Form and Function of the Human Pupil”, 1994-95; “Analysis of Pupil Dilation”, 1995-96. (Role: P.I.)
  • NSF Grant BNS -85-19267, “Visual Control of Fixation and Slow Eye Movements”, 1986-88. (Role: H.Wyatt & J. Pola Co-Investigators)
  • NSF Grant BNS-84-6403, “Control of Smooth Pursuit Eye Movements in the Alert Monkey” (Doctoral Dissertation Research), 1984-86. (Role: J. Pola, C. Neary & H. Wyatt Co-Investigators)
  • NIH/NEI Grant EY-02878, “The Mechanism of Smooth Pursuit Eye Movements”, 1979-84. (Role: J. Pola & H. Wyatt Co-Investigators)
  • Optometric Center of New York Foundation, “Analysis of the Pupillary Light Reflex”, 1978-79. (Role: P.I.)

  • “Apparatus and Method for Assessing Retinal Damage” (Domestic Patent granted; International Patents applied for; technology licensed.)
  • “A Method for Improving the Accuracy of Video-Based Eyetrackers”
  • “A Method For Reducing Test-Retest Variability In Tests Of Visual Fields”

(Provisional Patent applications)

  • Wyatt H.J. (2011) Automated perimetry: using gaze-direction data to improve the estimate of scotoma edges. Investigative Ophthalmology & Visual Science 52: 5818–5823
  • Wyatt H.J. (2010) The human pupil and the use of video-based eyetrackers. Vision Research 50: 1982–1988
  • Shyu, B. and Wyatt H.J. (2009) The appearance of the human eye: optical contributions to the “limbal ring”. Optometry and Vision Science 86: E1069-E1077.
  • Chen Y., Wyatt H.J., Swanson W.H and Dul M.W. (2008) Rapid pupil-based assessment of glaucomatous damage. Optometry and Vision Science 85: 471-481.
  • Wyatt H.J., Dul M.W. and Swanson W.H. (2007) Variability of visual field measurements is correlated with the gradient of visual sensitivity. Vision Research. 47: 925-936. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094527/
  • Chen Y., Wyatt H.J. and Swanson W.H. (2005) Pupillary evaluation of retinal asymmetry: development and initial testing of a technique. Vision Research 45: 2549-2563. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1633710/
  • Chepaitis A., Griffiths F., Wyatt H.J. and O'Connell W.F. (2004) Evaluation of tactile fonts for use by a visually impaired elderly population. Visual Impairment Research 6: 111-134.
  • Chen Y. and Wyatt H.J. (2004) Effects of changing the direction of gravity on sector pupil dilations. Optometry and Vision Science 81: 629-635.
  • Wyatt H.J. (2004) Modelling transport in the anterior segment of the eye. Optometry and Vision Science 81: 272-282. [Erratum: Optometry and Vision Science 81: 478.]
  • Wyatt H.J. and Lustgarten M. (2001) Probing anterior segment kinetics with focally applied mydriatics.Journal of Ocular Pharmacology & Therapeutics 17: 461-473.
  • Pola J. and Wyatt H.J. (2001) Offset dynamics of human smooth pursuit eye movements: effects of varying feedback following target jump ahead of the fovea. Vision Research 41: 655-669.
  • Wyatt H.J., Hall E.C. and Engber K. (2000) Representation of simple graphs in virtual tactile space. Journal of Visual Impairment & Blindness 94: 713-716.
  • Wyatt H.J. (2000) A minimum-wear-and-tear meshwork for the iris. Vision Research 40: 2167-2176.
  • Wyatt H.J. (1998) Detecting saccades with jerk. Vision Research38:2147-2153.
  • Pola J. and Wyatt H.J. (1997) Offset dynamics of human smooth pursuit eye movements: effects of target presence and subject intention. Vision Research 37:2579-2595.
  • Aquilante K., Wyatt H. and Yager D. (1997) Eye movements of congenital nystagmats are slower during RSVP reading than during PAGE reading. In: Non-invasive Assessment of the Visual system (Yager D., ed) Optical Society of America, Trends in Optics and Photonics, 11: 127-131.
  • Wyatt H.J. (1996) Ocular pharmacokinetics and convectional flow: evidence from spatio-temporal analysis of mydriasis. Journal of Ocular Pharmacology & Therapeutics 12: 441-459.
  • Wyatt H.J. and Fisher R.F. (1995) A simple view of age-related changes in the shape of the lens of the human eye. Eye 9: 772-775.
  • Wyatt H.J., Pola J., Lustgarten M. and Aksionoff E. (1995) OKN suppression by fixation of a stabilized target: the effect of OKN-stimulus predictability. Vision Research 35: 2903-2910.
  • Wyatt H.J. (1995) The form of the human pupil. Vision Research 35: 2021-2036.
  • Pola J., Wyatt H.J. and Lustgarten M. (1995) Visual fixation of a target and suppression of OKN: effects of varying target feedback. Vision Research 35: 1079-1087.
  • Pola J. and Wyatt H.J. (1994) Smooth pursuit eye movement: target velocity starts it; target position stops it. In: Contemporary Ocular Motor and Vestibular Research: A Tribute to David A. Robinson (Fuchs A.F., Brandt T., Büttner U. and Zee D., eds.). George Thieme Verlag, Stuttgart (pp. 142-148).
  • Wyatt H.J., Pola J., Fortune B. and Posner M. (1994) Smooth pursuit eye movements with imaginary targets defined by extrafoveal cues. Vision Research 34: 803-820.
  • Pola J. and Wyatt H.J. (1993) Role of Attention and Cognitive Processes. In: Visual Motion and its Role in the Stabilization of Gaze (Wallman J. and Miles F.A., eds.). (Reviews of Oculomotor Research, Vol. 5), Elsevier (pp 371-392).
  • Wyatt H.J. (1993) Application of a simple mechanical model of accommodation to the aging eye. Vision Research 33: 731-738.
  • Pola J., Wyatt H.J. and Lustgarten M. (1992) Suppression of optokinesis by a stabilized target: effects of instruction and stimulus frequency. Perception and Psychophysics 52: 186-200.
  • Wyatt H.J. (1992) A hypothesis concerning retinotopy in the optic nerve head and its relationship to perimetry. Clinical Vision Sciences 7:53-61.
  • Wyatt H.J. (1991) Modelling the kinetics of topically-applied ophthalmic agents. Optometry and Vision Science 68: 663-665.
  • Pola J. and Wyatt H.J. (1991) The smooth pursuit eye movement system: response characteristics, stimuli, and mechanisms. In: Vision and Visual Dysfunction; Volume 8: Eye Movements (Carpenter R.H.S., ed), MacMillan, London (pp 138-156).
  • Ettinger E.R., Wyatt H.J. and London R. (1991) Anisocoria: variation and clinical observation with different conditions of illumination and accommodation. Investigative Ophthalmology & Visual Science 32: 501-509.
  • Wyatt H.J., Pola J. and Lustgarten M. (1989) The oculomotor “twitch” - a transient response to target motion. Experimental Brain Research 76: 581-592.
  • Pola J. and Wyatt H.J. (1989) The perception of target motion during smooth pursuit eye movements in the open-loop condition: the characteristics of retinal and extraretinal signals. Vision Research 29: 471-483.
  • Wyatt H.J. and Pola J. (1988) Predictive behavior of optokinetic eye movements. Experimental Brain Research 73: 615-626.
  • Wyatt H.J., Pola J. and Lustgarten M. (1988) “Passive suppression” of optokinesis by stabilized targets. Vision Research 28: 1023-1029.
  • Wyatt H.J. (1988) Manual of Visual Anatomy and Physiology, New York, Fairchild.
  • Wyatt H.J. (1988) Some aspects of the mechanics of accommodation. Vision Research 28: 75-86.
  • Wyatt H. J. and Pola J. (1987) Smooth eye movements with step-ramp stimuli: the influence of attention and stimulus extent. Vision Research 27:1565-1580.
  • Neary C., Pola J. and Wyatt H.J. (1986) Target position: a stimulus for smooth pursuit eye movements in the monkey. In: Eye Movements from Physiology to Cognition, Edited Proceedings of the Third European Conference on Eye Movements (Dourdan, France, 1985); Eds. O'Regan J.K. and Levy-Schoen A., Elsevier North Holland, Amsterdam.
  • Pola J. and Wyatt H.J. (1985) Active and passive smooth eye movements: effects of stimulus size and location. Vision Research 25: 1063-1076.
  • Wyatt H.J. and Pola J. (1984) A mechanism for suppression of optokinesis. Vision Research 24: 1931-1945.
  • Wyatt H.J. and Pola J. (1983) Smooth pursuit eye movements under open-loop and closed-loop conditions. Vision Research 23: 1121-1131.
  • Wyatt H.J. and Musselman J.F. (1981) Pupillary light reflex in humans: evidence for an unbalanced pathway from nasal retina, and for signal cancellation in brainstem. Vision Research 21: 513-535.
  • Wyatt H.J. and Pola J. (1981) Slow eye movements to eccentric targets. Investigative Ophthalmology & Visual Science 21: 477-483.
  • Pola J. and Wyatt H.J. (1980) Target position and velocity: the stimuli for smooth pursuit eye movements. Vision Research 20: 523-534.
  • Wyatt H.J. and Pola J. (1979) The role of perceived motion in smooth pursuit eye movements. Vision Research 19: 613-618.
  • Wyatt H.J. (1978) Naso-temporal overlap and visual field sparing. Investigative Ophthalmology & Visual Science 17: 1128-1130.
  • Wyatt H.J. (l978) Purkinje's methods for visualizing the internal retinal circulation: a look at the source. Vision Research 18: 875-877.
  • Caldwell J., Daw N.W. and Wyatt H.J. (1978) Effects of picrotoxin and strychnine on rabbit retinal ganglion cells: lateral interaction for cells with more complex receptive fields. Journal of Physiology 276: 277-298.
  • Daw N.W. and Wyatt H.J. (1976) Kittens reared in a unidirectional environment: evidence for a critical period. Journal of Physiology 257: 155-170.
  • Wyatt H.J. and Daw N.W. (1976) Specific effects of neurotransmitter antagonists on ganglion cells in rabbit retina. Science 191: 204-205.
  • Wyatt H.J. with Ellis R.A. (l975) A special-purpose computer system for on-line generation and display of “random-dot” stimuli for stereoscopic vision experiments. In: Proceedings of the Second Annual Conference on Computer Graphics and Interactive Techniques, June 25-27, l975, Bowling Green, Ohio. (Publ. Assoc. for Computing Machinery.) pp.111-114.
  • Wyatt H.J. and Daw N.W. (1975) Directionally sensitive ganglion cells in the rabbit retina: specificity for stimulus direction, size and speed. Journal of Neurophysiology 38: 613-626.
  • Daw N.W. and Wyatt H.J. (1974) Raising rabbits in a moving visual environment: an attempt to modify directional sensitivity in the retina. Journal of Physiology 240: 309-330.
  • Wyatt H.J. (1974) Singly and doubly contingent after-effects involving color, orientation and spatial frequency. Vision Research 14: 1185-1193.
  • Wyatt H.J. (1972) Scotopic vision: an unexpected threshold elevation produced by dark stimuli. Vision Research 12: 2147-2150.
  • Wyatt H.J. (1971) Spatial interactions in adaptation of human scotopic vision. Ph.D. Thesis, University of California, Berkeley.

(1994) Physiology of the the Eye - an Introduction to the Vegetative Functions. (2nd ed) Fatt I and Weissman B.A. Reviewed in: Optometric Education 19:63.

  • “Retest Variability and the Gradient of the Visual Field: Blind Spot vs. Scotoma.” H.J. Wyatt, J.Chan, W.H. Swanson, & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 27-May 1, 2008 (abstract accepted).
  • “Retinal asymmetry in patients with glaucoma: comparison of pupillary light reflex and nerve fiber layer thickness.” H.J. Wyatt, H. McLeod, R. Madonna, M.W. Dul & W.H. Swanson. A.A.O. Fall Meeting, Tampa, Florida, Oct. 24-27, 2007.
  • “Report on a pupil-based approach to glaucoma testing.” H.J. Wyatt, W.H. Swanson, M. Dul & Y. Chen. North American Perimetry Society, Skaeateles, NY, Sept 26-27, 2007.
  • “Retest variability is correlated with gradient of the visual field near the normal physiological blind spot.” H.J. Wyatt, J. Lam, J. Chan, W.H. Swanson & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 5-9, 2007.
  • “Variability of visual field measurements is correlated with the gradient of sensitivity.” H.J. Wyatt and M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 4, 2006.
  • “Variability of visual field measurements is correlated with the gradient of sensitivity.” H.J. Wyatt and M.W. Dul. North American Perimetry Society, Skaeateles, NY, Sept 22-23, 2005.
  • AA rapid test to evaluate upper/lower retinal asymmetry in glaucomatous optic neuropathy using the pupil light reflex.@ Y.Chen, H.J. Wyatt, W.H. Swanson & M.W. Dul. 26th Pupil Colloquium, Bear Mountain, NY, Aug 22-26, 2005.
  • “Use of response amplitude to complement response balance in a pupil based system for assessing glaucomatous damage.” H.J. Wyatt, Y. Chen, W.H. Swanson & M.W. Dul. 26th Pupil Colloquium, Bear Mountain, NY, Aug22-26, 2005.
  • ”Rapid assessment of glaucomatous damage with the pupillary light reflex: asymmetry and amplitude measures of abnormality“ Y. Chen, H.J. Wyatt, W.H. Swanson & M.W. Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 1-5, 2005.
  • “Comparison of the elia and braille tactile alphabets for adult visually impaired readers” A.J. Chepaitis, A.Griffiths, H.J. Wyatt & K.Aquilante. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 1-5, 2005.
  • “A new pupil-based approach to glaucoma testing: design and initial studies” H.J. Wyatt, Y. Chen, W.H. Swanson & M.W. Dul. A.A.O. Fall Meeting, Tampa, Florida, Dec 9-12, 2004.
  • “A new pupil-based approach to glaucoma testing: application of the method to glaucoma patients” Y.Chen, H.J. Wyatt, W.H. Swanson & M.Dul. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004.
  • “A new pupil-based approach to glaucoma testing: design and initial testing” H.J. Wyatt, Y.Chen & W.H. Swanson. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004.
  • “Reading with simulated rp: effects of visual field size” K.Ma, H.Wyatt, D.Yager & D.D. Lin. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 25-29, 2004.
  • “A new approach to assessing glaucomatous damage using pupillometry.” H.J. Wyatt, Y. Chen & W.H. Swanson. 25th Pupil Colloquium, Crete, Greece, September 10-14, 2003.
  • “Testing the ability of seniors to learn and read tactile alphabets.” A.J. Chepaitis, A.F. Griffiths, H.J. Wyatt & W.F. O'Connell. A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 4-9, 2003.
  • “Modeling anterior segment kinetics” H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, May 5-10, 2002.
  • “Anterior segment pharmacokinetics: how things move around” H.J. Wyatt, The 24th Pupil Colloquium, Asilomar, California, September 7-11, 2001.
  • “Modeling the mydriatic pathway to the pupil.” H.J. Wyatt & Y. Chen, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 29-May 4, 2001.
  • “Nonlinear iris stretch and an iris 'minimum-wear-and-tear' meshwork.” H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.
  • “Normal subjects reading rsvp text slowly make saccades.” K. Aquilante, H.J. Wyatt, D. Yager & R.A. Morris, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.
  • “Using sector pupil dilation and head tilt to map anterior segment kinetics and convectional flow.” Y. Chen & H.J. Wyatt, A.R.V.O. Spring Meeting, Ft. Lauderdale, Florida, April 30-May 5, 2000.