Jose-Manuel Alonso, MD, PhD
Biological Sciences
SUNY College of Optometry
33 West 42nd Street New York, NY 10036

Research Description

 

Functional Circuitry of the Visual Thalamus and Cortex

My laboratory is interested in understanding how the brain processes visual information.  We pursue this general goal by investigating how neurons connect to each other and the role of these connections in constructing precise representations of the visual world in the brain. Most of our work focuses on two main structures early in the visual pathway: the thalamus and the primary visual cortex. These two structures have the most detailed representation of visual space in the brain and constitute the entrance of visual information to the cerebral cortex. Disruption of the circuits from thalamus and primary visual cortex leads to cortical blindness: a lack of vision that can not be treated by restoring eye function. Disruption of thalamic and cortical circuits can result as a consequence of eye disease, neurodegenerative disorders and brain insults.

In my laboratory, we investigate the neuronal circuits of thalamus and visual cortex by using state-of-the-art technology that includes multielectrode/imaging recording from neuronal populations and computational modeling. Specific approaches are: a) study visual responses from multiple neurons under different stimulus conditions; b) identify neurons that are directly connected and study the response properties at the two poles of the connection; c) measure synchronous firing generated by different types of neurons and investigate its role in visual processing; d) study the role of populations of neurons in encoding visual information; e) study the role of alertness, visual attention and task difficulty in modulating neuronal responses; f) study changes in thalamo-cortical circuits that result from the local inactivation (or stimulation) of small groups of neurons. Our laboratory is proud to collaborate with other outstanding research teams within and outside SUNY Optometry. Two of our most productive, current collaborations are with Prof. Swadlow at the University of Connecticut, Department of Psychology and with Prof. Stanley at Georgia Tech and Emory University, Department of Biomedical Engineering.

A better understanding of how neural circuits process visual information is essential to develop new strategies for the treatment and prevention of visual disorders. The long-term goal of our laboratory is to generate breakthroughs that make these new treatment and prevention approaches possible.

Education

 

Neuroscience, Universidad Autónoma de Madrid, Madrid, Spain, PhD, 1992

Universidad de Santiago de Compostela, Santiago, Spain, MS, 1989

Universidad de Santiago de Compostela, Santiago, Spain, MD, 1989

 

Professional Positions

 
  • 2007-Present: Professor, Dept. of Biological Sciences, SUNY College of Optometry, New York, NY

  • 2004-2007: Associate Professor with tenure, Dept. of Biological Sciences, SUNY College of Optometry, New York, NY

  • 2002-Present: Associate Professor, Dept. of Biological Sciences, SUNY College of Optometry, New York, NY

  • 1999-2001: Assistant Professor, Dept. of Psychology, University of Connecticut, Storrs, CT

  • 1995-1999: Research Associate, Laboratory of Neurobiology, Rockefeller University, New York, NY

  • 1993-1995: Postdoctoral Fellow with Torsten N. Wiesel (Nobel prize winner) and Clay Reid, Laboratory of Neurobiology, Rockefeller University, New York, NY

Research Awards and Honors

 
  • 2010-2015: P.I. NIH RO1 EY02067901

  • 1999-2017: P.I. NIH RO1 EY05253

  • 2009-2012: P.I. NSF IIS 0904727

  • 2008-2010: P.I. NIH R21 NS059753

  • 2003-2008: P.I. NIH RO3 EY14345

  • 2001-2004: CoPI. NIH RO3 EY13788

  • 2006-2006: Faculty Member, Faculty of 1000 Biology SUNY Chancellor’s award for Excellence in Scholarship and Creative Activities

  • 2003: SUNY Chancellor’s award for Research Excellence

  • 1995-1996: Revson Fellowship

  • 1993-1994: Fulbright Fellowship
  • 1990-1992: Fellowship from Formación de Personal Investigador del Ministerio de Educación y Ciencia

  • 1989-1990: Fellowship from Diputacion Provincial de Galicia

  • 1985-1989: Fellowship from Xunta de Galicia

Research Interests

 
  • Neural circuitry of the visual cortex
  • Function of thalamic and cortical circuits in receptive field construction
  • The neural circuitry of visual attention

 

Publications

 

Lashgari, R., X. Li, Y. Chen, J. Kremkow, Y. Bereshpolova, H. A. Swadlow and J. M. Alonso (2012). Response properties of local field potentials and neighboring single neurons in awake primary visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 32(33): 11396-413. PMID: 22895722.  PMCID: 3436073.

Stanley, G. B., J. Jin, Y. Wang, G. Desbordes, Q. Wang, M. J. Black and J. M. Alonso (2012). Visual Orientation and Directional Selectivity through Thalamic Synchrony. The Journal of neuroscience : the official journal of the Society for Neuroscience 32(26): 9073-88. PMID: 22745507.  PMCID in process.

Butts, D. A., C. Weng, J. Jin, J. M. Alonso and L. Paninski (2011). Temporal precision in the visual pathway through the interplay of excitation and stimulus-driven suppression. The Journal of Neuroscience 31(31): 11313-27. PMID: 21813691.  PMCID: 3197857.

Bereshpolova, Y., C. R. Stoelzel, J. Zhuang, Y. Amitai, J. M. Alonso and H. A. Swadlow (2011). Getting drowsy? Alert/nonalert transitions and visual thalamocortical network dynamics. The Journal of Neuroscience  31(48): 17480-7. PMID: 22131409.  PMCID (in process).

Jin, J., Y. Wang, R. Lashgari, H. A. Swadlow and J. M. Alonso (2011). Faster thalamocortical processing for dark than light visual targets. The Journal of Neuroscience 31(48): 17471-9. PMID: 22131408.  PMCID (in process).

Jin, J., Y. Wang, H. A. Swadlow and J. M. Alonso (2011). Population receptive fields of ON and OFF thalamic inputs to an orientation column in visual cortex. Nat Neurosci 14(2): 232-8. PMCID. (in process). News and Views associated to this paper: Ringach, D. L. (2011). You get what you get and you don't get upset. Nat Neurosci 14(2): 123-4.

Komban, S. J., J. M. Alonso and Q. Zaidi (2011). Darks are processed faster than lights. The Journal of Neuroscience  31(23): 8654-8. PMID: 21653869.  PMCID: 3263349.

Butts, D. A., G. Desbordes, C. Weng, J. Jin, J. M. Alonso and G. B. Stanley (2010). The episodic nature of spike trains in the early visual pathway. Journal of Neurophysiology 104(6): 3371-87. PMID: 20926615.  PMCID: 3007659.

Desbordes, G., J. Jin, J. M. Alonso and G. B. Stanley (2010). Modulation of temporal precision in thalamic population responses to natural visual stimuli. Frontiers in systems neuroscience 4: 151. PMID: 21151356.  PMCID: 2992450.

Chen, Y., S. Anand, S. Martinez-Conde, S. L. Macknik, Y. Bereshpolova, H. A. Swadlow and J. M. Alonso (2009). The linearity and selectivity of neuronal responses in awake visual cortex. J Vis 9(9): 12 1-17. Comments associated to this paper: D. M. Snodderly, I. Kagan, M. Gur (2010) Linearity and selectivity of neuronal responses in awake visual cortex. Importance of the cell sample. Published September 14, 2010. J.M. Alonso, Y. Chen, H.A. Swadlow (2010). Elusive bimodality of response linearity in primary visual cortex. . Published October 19, 2010.

Alonso, J. M. (2009). My recollections of Hubel and Wiesel and a brief review of functional circuitry in the visual pathway. J Physiol 587(Pt 12): 2783-90.

Alonso, J.M, Chen, Y. (2009) Receptive field. Scholarpedia, 4(1):5393

Yeh, C. I., C. R. Stoelzel, C. Weng and J. M. Alonso (2009). Functional consequences of neuronal divergence within the retinogeniculate pathway. J Neurophysiol 101(4): 2166-85. PubMed ID:19176606.

Swadlow, H. A. and J. M. Alonso (2009). Spikes are making waves in the visual cortex. Nat Neurosci 12(1): 10-1. PubMed ID:19107144.

Alonso, J. M., C. I. Yeh and C. R. Stoelzel (2008). Visual stimuli modulate precise synchronous firing within the thalamus. (Special Issue in memory of Mircea Steriade). Thalamus Relat Syst 4(1): 21-34. PubMed ID:19011698.

Desbordes, G., J. Jin, C. Weng, N. A. Lesica, G. B. Stanley and J. M. Alonso (2008). Timing precision in population coding of natural scenes in the early visual system. PLoS Biol 6(12): e324. PubMed ID:19090624.

Jin, J. Z., C. Weng, C. I. Yeh, J. A. Gordon, E. S. Ruthazer, M. P. Stryker, H. A. Swadlow and J. M. Alonso (2008). On and off domains of geniculate afferents in cat primary visual cortex. Nat Neurosci 11(1): 88-94. PubMed ID:18084287. (Cover of this Nature Neuroscience issue and selected cover to represent Nature Neuroscience in 2009 Calendar of Nature journals).

Chen, Y., Martinez-Conde, S., Macknik, S.L., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. (2008) Task difficulty modulates the activity of specific neuronal populations in primary visual cortex. Nat Neurosci 11 (8): 975-982.  (Featured in News and Views of Nature Neuroscience by John Reynolds, in Faculty 1000 by John Reynolds and in a Science News article (25, 2009, 23-25) by Laura Sanders titled 'It's not magic, it’s neuroscience'.) Click here for supplementary information

Butts, D.A., C. Weng, J. Jin, C.I. Yeh, N.A. Lesica, J.M. Alonso and G.B. Stanley (2007) Temporal precision in the neural code and the time scales of natural vision. Nature 449:92-95.

Lesica, N. A., J. Jin, C. Weng, C. I. Yeh, D. A. Butts, G. B. Stanley and J. M. Alonso (2007). "Adaptation to Stimulus Contrast and Correlations during Natural Visual Stimulation." Neuron 55(3): 479-91. Click here for supplementary information

Alonso, J. M. (2007). El talamo y la vision. Investigacion y Ciencia 22: 26-32.

Alonso, J. M. (2006). Neurons find strength through synchrony in the brain. Science 312: 1604-05.

Alonso, J. M. (2006). La vía visual cien años después de Ramón y Cajal. Santiago Ramón y Cajal. Cien años después. A. G. y. A. Ferrús. les Illes Balears, Editorial Pirámide - Universitat de les Illes Balears: 233-255.

Alonso, J. M., C. I. Yeh, C. Weng and C. Stoelzel (2006). Chapter 1 Retinogeniculate connections: a balancing act between connection specificity and receptive field diversity. Prog Brain Res 154: 3-13.

Bezdudnaya, T., M. Cano, Y. Bereshpolova, C. R. Stoelzel, J. M. Alonso and H. A. Swadlow (2006). Thalamic Burst Mode and Inattention in the Awake LGNd. Neuron 49(3): 421-32.
Click here for supplementary information

Cano, M., T. Bezdudnaya, H. A. Swadlow and J. M. Alonso (2006). Brain state and contrast sensitivity in the awake visual thalamus. Nat Neurosci 9(10): 1240-2.Supplementary methods

Lesica, N. A., C. Weng, J. Jin, C. I. Yeh, J. M. Alonso and G. B. Stanley (2006). Dynamic Encoding of Natural Luminance Sequences by LGN Bursts. PLoS Biol 4(7): e209.

Veredas FJ, Vico FJ, Alonso JM (2006) Evolving networks of integrate and fire neurons. Neurocomputing 69:1561-1569.

Alonso, J. M. (2005). "Building better models of visual cortical receptive fields." Neuron 46(6): 842-4.

Alonso, J. M. and H. A. Swadlow (2005). "Thalamocortical specificity and the synthesis of sensory cortical receptive fields." J Neurophysiol 94(1): 26-32.

Martinez, L. M., Q. Wang, R. C. Reid, C. Pillai, J. M. Alonso, F. T. Sommer and J. A. Hirsch (2005). "Receptive field structure varies with layer in the primary visual cortex." Nat Neurosci 8(3): 372-9.

Veredas, F. J., F. J. Vico and J. M. Alonso (2005). "Factors determining the precision of the correlated firing generated by a monosynaptic connection in the cat visual pathway." J Physiol 567(Pt 3): 1057-78.

Weng, C., C. I. Yeh, C. R. Stoelzel and J. M. Alonso (2005). "Receptive field size and response latency are correlated within the cat visual thalamus." J Neurophysiol 93(6): 3537-47.

Veredas, F. J., F. J. Vico and J. M. Alonso (2004). "A computational tool to simulate correlated activity in neural circuits." J Neurosci Methods 136(1): 23-32.

Hirsch, J. A., L. M. Martinez, C. Pillai, J. M. Alonso, Q. Wang and F. T. Sommer (2003). "Functionally distinct inhibitory neurons at the first stage of visual cortical processing." Nat Neurosci 6(12): 1300-8.

Martinez, L. M. and J. M. Alonso (2003). "Complex receptive fields in primary visual cortex." Neuroscientist 9(5): 317-31.

Yeh, C. I., C. R. Stoelzel and J. M. Alonso (2003). "Two different types of Y cells in the cat lateral geniculate nucleus." J Neurophysiol 90(3): 1852-64.

Alonso, J. M. (2002). "Neural connections and receptive field properties in the primary visual cortex." Neuroscientist 8(5): 443-56.

Alonso-Lopez, J. M. (2002). "[Visual pathways: a set of time-saving strategies]." Rev Neurol 35(5): 446-51.

Hirsch, J. A., L. M. Martinez, J. M. Alonso, K. Desai, C. Pillai and C. Pierre (2002). "Synaptic physiology of the flow of information in the cat's visual cortex in vivo." J Physiol 540(Pt 1): 335-50.

Martinez, L. M., J. M. Alonso, R. C. Reid and J. A. Hirsch (2002). "Laminar processing of stimulus orientation in cat visual cortex." J Physiol 540(Pt 1): 321-33.

Reid, R. C., J. M. Alonso and W. M. and Usrey (2002). Integration of thalamic inputs to cat primary visual cortex. The cat primary visual cortex. B. R. Payne and A. Peters, Academic Press. 8: 319-337.

Alonso, J. M., W. M. Usrey and R. C. Reid (2001). "Rules of connectivity between geniculate cells and simple cells in cat primary visual cortex." J Neurosci 21(11): 4002-15.

Martinez, L. M. and J. M. Alonso (2001). "Construction of complex receptive fields in cat primary visual cortex." Neuron 32(3): 515-25.

Cecchi, G. A., M. Sigman, J. M. Alonso, L. Martinez, D. R. Chialvo and M. O. Magnasco (2000). "Noise in neurons is message dependent." Proc Natl Acad Sci U S A 97(10): 5557-61.

Usrey, W. M., J. M. Alonso and R. C. Reid (2000). "Synaptic interactions between thalamic inputs to simple cells in cat visual cortex." J Neurosci 20(14): 5461-7.

Alonso, J. M. and L. M. Martinez (1998). "Functional connectivity between simple cells and complex cells in cat striate cortex." Nat Neurosci 1(5): 395-403.

Dan, Y., J. M. Alonso, W. M. Usrey and R. C. Reid (1998). "Coding of visual information by precisely correlated spikes in the lateral geniculate nucleus." Nat Neurosci 1(6): 501-7.

Hirsch, J. A., J. M. Alonso, R. C. Reid and L. M. Martinez (1998). "Synaptic integration in striate cortical simple cells." J Neurosci 18(22): 9517-28.

Hirsch, J. A., C. A. Gallagher, J. M. Alonso and L. M. Martinez (1998). "Ascending projections of simple and complex cells in layer 6 of the cat striate cortex." J Neurosci 18(19): 8086-94.

Alonso, J. M., W. M. Usrey and R. C. Reid (1996). "Precisely correlated firing in cells of the lateral geniculate nucleus." Nature 383(6603): 815-9.

Gonzalez, F., J. M. Alonso, J. L. Relova and R. Perez (1996). "Receptive field asymmetries and sensitivity to random dot stereograms." Arch Ital Biol 134(2): 169-84.

Reid, R. C. and J. M. Alonso (1996). "The processing and encoding of information in the visual cortex." Curr Opin Neurobiol 6(4): 475-80.

Hirsch, J. A., J. M. Alonso and R. C. Reid (1995). "Visually evoked calcium action potentials in cat striate cortex." Nature 378(6557): 612-6.

Reid, R. C. and J. M. Alonso (1995). "Specificity of monosynaptic connections from thalamus to visual cortex." Nature 378(6554): 281-4.

Cudeiro, J., C. Rivadulla, R. Rodriguez, S. Martinez-Conde, C. Acuna and J. M. Alonso (1994). "Modulatory influence of putative inhibitors of nitric oxide synthesis on visual processing in the cat lateral geniculate nucleus." J Neurophysiol 71(1): 146-9.

Alonso, J. M., J. Cudeiro, R. Perez, F. Gonzalez and C. Acuna (1993). "Influence of layer V of area 18 of the cat visual cortex on responses of cells in layer V of area 17 to stimuli of high velocity." Exp Brain Res 93(2): 363-6.

Alonso, J. M., J. Cudeiro, R. Perez, F. Gonzalez and C. Acuna (1993). "Orientational influences of layer V of visual area 18 upon cells in layer V of area 17 in the cat cortex." Exp Brain Res 96(2): 212-20.

Gonzalez, F., F. Krause, R. Perez, J. M. Alonso and C. Acuna (1993). "Binocular matching in monkey visual cortex: single cell responses to correlated and uncorrelated dynamic random dot stereograms." Neuroscience 52(4): 933-9.

Gonzalez, F., J. L. Relova, R. Perez, C. Acuna and J. M. Alonso (1993). "Cell responses to vertical and horizontal retinal disparities in the monkey visual cortex." Neurosci Lett 160(2): 167-70.

Gonzalez, F., R. Perez, J. M. Alonso, J. L. Labandeira-Garcia and C. Acuna (1992). "Responses of visual single cells in the superior colliculus of the albino rat to bright bars." Arch Ital Biol 130(4): 249-61.

Gonzalez, F., R. Perez, C. Acuna, J. M. Alonso and J. L. Labandeira-Garcia (1991). "Contrast responses to bright slits of visual cells in the superior colliculus of the albino rat." Int J Neurosci 58(3-4): 255-9.

Acuna, C., J. Cudeiro, F. Gonzalez, J. M. Alonso and R. Perez (1990). "Lateral-posterior and pulvinar reaching cells--comparison with parietal area 5a: a study in behaving Macaca nemestrina monkeys." Exp Brain Res 82(1): 158-66.

Cudeiro, J., F. Gonzalez, R. Perez, J. M. Alonso and C. Acuna (1989). "Does the pulvinar-LP complex contribute to motor programming?" Brain Res 484(1-2): 367-70.

 

Conference Presentations and Abstracts

 

Bereshpolova, Y.I., Stoelzel, C.R., Zhuang, J., Amitai, Y., Alonso, J.M., Swadlow, H.A. Getting drowsy? Alert/non-alert transitions and visual thalamocortical network dynamics. .  Program No. 484.16. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online.

Lashgari, R., Li, X., Chen, Y., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. Contrast response functions of single neurons and local field potentials in primary visual cortex of awake primates.  Program No. 674.9. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online.

Li, X., Lashgari, R., Chen, Y., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. Slowly-progressing visual adaptation of local field potential and single neuron activity in primary visual cortex.  Program No. 73.9. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online.

Wang, Y., Jin, J. Lashgari, R. Alonso, J.M. Columnar organization of on/off receptive field structure in primary visual cortex. Program No. 277.15. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online.

Zhuang, J., Bereshpolova, Y., Stoelzel, C. Huff, J., Alonso, J.M., Swadlow, H.A. Getting drowsy? Alert/non-alert transitions and response properties in layer 4 of V1. Program No. 484.15. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online.

Bereshpolova, Y.I., Stoelzel, C.R., Zhuang, J., Amitai, Y., Alonso, J.M., Swadlow, H.A. (2009) Brain state and thalamocortical network dynamics: Stability in the face of shifting synaptic inputs. Program No. 353.25. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Chen, Y., Anand, S., Martinez-Conde, S., Macknik, S., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. (2009) The linearity and selectivity of neuronal responses in awake visual cortex.  Program No. 166.1. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Desbordes, G., Jin, J., Alonso, J.M., Stanley, G.B. (2009) A generalized linear model captures the fine temporal precision of thalamic responses to visual stimuli.  Program No. 849.8. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.
Jin, J., Wang, Y., Lashgari, R., Swadlow, H.A., Alonso, J.M. (2009) Visual responses are faster in OFF than ON visual channels. Program No. 848.5. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Komban, J., Alonso, J.M., Zaidi, Q. (2009) ON and OFF visual channels: differences in spatial resolution and contrast sensitivity.  Program No. 166.22. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Polosecki, P., Komban,J.S., Chen, Y., Jin, J., Wang, Y. Lashgari, R., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. (2009) The receptive fields from local field potentials are similar in size to those from multiunit and single unit activity. Program No. 261.13. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Stanley, G.B., Black, M.J., Desborders, G., Jin, J., Wang, Y., Alonso, J.M. (2009). Decoding visual motion from correlated firing of thalamic neurons. Program No. 849.10. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Wang, Y., Jin, J., Lashgari, R., Alonso, J.M. (2009) Topographic organization of on and off neuronal clusters in visual cortex.  Program No. 261.5. 2009 Neuroscience meeting planner. Chicago, IL: Society for Neuroscience, 2009. Online.

Desbordes, G., Jin, J., Weng, C., Lesica, N.A., Stanley, G.B., Alonso, J.M. (2009) Timing precision in population coding of natural scenes in the early visual system. COSYNE 2009, No. 128.

Stanley, G., Black, M., Lewis, J.P., Desbordes, G., Jin, J., Alonso, J.M. (2009). Population coding of ground truth motion in natural scenes in the early visual system. COSYNE 2009, No. 257.

Desbordes, G., Jin, J., Weng, C., Lesica, N.A., Butts, D.A., Stanley, G.B., Alonso, J.M. (2008) Invariance of spike timing precision within neural populations in the early visual system. Program No. 459.21. 2008 Neuroscience meeting planner. Washington, DC: Society for Neuroscience, 2008. Online

Jin, J., Wang, Y., Chen, Y., Swadlow, H.A., Alonso, J.M. (2008) Receptive field clustering of on and off geniculate afferents within a cortical orientation domain predicts the domain orientation preference. Program No. 769.3. 2008 Neuroscience meeting planner.Washington, DC: Society for Neuroscience, 2008. Online.

Chen, Y., Martinez-Conde, S., Macknik, S., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. (2007) Attentional load modulates the activity of distinct populations of neurons within primary visual cortex. Program No. 931.18. 2007 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2007. Online.

Besbordes, G., Weng, C., Jin, J., Butts, D.A., Alonso, J.M., Stanley, G.B. (2007) How correlated is the neural code entering primary visual cortex? Program No. 615.1. 2007 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2007. Online.

Butts, D.A., Jin, J., Weng, C., Lesica, N.A., Stanley, G.B., Alonso, J.M., Paninski, L. (2007) Tuned ‘suppression’ in the LGN underlies millisecond precision and has significant implications for visual coding. Program No. 615.3. 2007 Neuroscience meeting planner.Atlanta, GA: Society for Neuroscience, 2007. Online.

Jin, J., Yeh, Weng, C., Anand, S., Swadlow, H.A., Alonso, J.M. (2007) Receptive field arrangement of thalamic afferents within an orientation domain in cat primary visual cortex. Program No. 920.10. 2007 Neuroscience meeting planner. San Diego, CA: Society for Neuroscience, 2007. Online.

Weng, C., Jin, J., Yeh, C.I., Alonso, J.M. (2007) Influence of contrast on the spatial frequency tuning of neuronal populations in the cat visual thalamus. Program No. 392.29. 2007 Neuroscience meeting planner. San Diego, CA: Society for Neuroscience, 2007. Online.

Butts, D.A., Weng, C., Jin, J., Yeh, C.I., Lesica, N.A., Alonso, J.M., Stanley, G.B. (2006) The role of temporal precision in the neural code and its relationship to the time scales of natural stimuli. Program No. 734.22. 2006 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2006. Online.

Chen, Y., Martinez-Conde, S., Macknik, S., Bereshpolova, Y., Swadlow, H.A., Alonso, J.M. (2006) Manual reaction time is strongly correlated with the occurrence of reflexive saccades but not with attentional modulations in V1. Program No. 548.1. 2006 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2006. Online.

Eisele, M., Weng, C., Jin, J.Z., Yeh, C.I., Alonso, J.M., Miller, K.D. (2006) Optimal encoding and the diversity of response properties in the visual thalamus. Program No. 11.7. 2006 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2006. Online.

Jin, J.Z., Weng, C., Yeh, C.I., Gordon, J.A., Ruthazer, E.S., Stryker, M.P., Swadlow, H.A., Alonso, J.M. (2006) On- and off-domains of geniculate afferents in cat primary visual cortex. Program No. 436.12. 2006 Neuroscience meeting planner. Atlanta, GA: Society for Neuroscience, 2006. Online.

Bezdudnaya, T., Cano, M., Alonso, J.M., Swadlow, H.A. (2005) Inattentive vision and ‘burst mode’ in awake subjects: temporal tuning in the LGNd. Program No. 506.11. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Butts, D.A., Weng, C., Jin, J.Z., Yeh, C.I., Lesica, N.A., Alonso, J.M., Stanley, G.B. (2005) Changes in functional properties of LGN neurons with contrast and their significance in information transmission. Program No. 855.3. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Cano, M., Bezdudnaya, T., Alonso, J.M., Swadlow, H.A. (2005) The contrast response function of the awake LGN is accurately scaled during state transitions. Program No. 506.10. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Chen, Y., Martinez-Conde, S., Macknik, Bereshpolova, Y., S., Swadlow, H., Alonso, J.M. (2005) Detection difficulty increases neuronal activity in primary visual cortex. Program No. 286.14. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Jin, J.Z., Weng, C., Yeh, C.I., Swadlow, H.A., Alonso, J.M. (2005) Synaptic impact of single geniculate afferents through the depth of cat primary visual cortex. Program No. 742.7. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Lesica, N.A., Weng, C., Jin, J.Z., Yeh, C.I., Butts, D.A., Alonso, J.M., Stanley, G.B. (2005) The effects of contrast adaptation during natural stimulation. Program No. 855.2. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

Bezdudnaya, T., Cano, M., Alonso, J.M., Swadlow, H.A. (2004) Temporal frequency tuning of excitatory and inhibitory neurons in alert and drowsy visual cortex. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 410.5, 2004.

Cano, M., Bezdudnaya, T., Swadlow, H.A., Alonso, J.M. (2004) Contrast sensitivity of excitatory and inhibitory neurons in alert and drowsy visual cortex. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 410.4, 2004.

Chen, Y., Martinez-Conde, S., Macknik, S., Swadlow, H., Alonso, J.M. (2004) Task difficulty modulates neuronal activity in primary visual cortex. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 157.7, 2004.

Jin, J.Z., Weng, C., Yeh, C.I., Alonso, J.M. (2004) Influence of contrast on the spatial properties of cells in the cat lateral geniculate nucleus. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 409.1, 2004.

Martinez, L.M., Alonso, J.M. (2004) A circuit split across the striate cortex determined by the influence of spike history on synaptic efficacy. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 984.9, 2004.

Yeh, C.I., Stoelzel, C.R., Weng, C., Alonso, J.M. (2004) Wiring specificity of the Y pathway in the cat lateral geniculate nucleus. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 CD-ROM: Program No. 409.2, 2004.

Bezdudnaya, T., Cano, M., Alonso, J.M., Swadlow, H.A. (2003) Temporal-frequency tuning and arousal in awake LGN. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2003 CD-ROM: Program No. 551.4, 2003.

Cano, M., Bezdudnaya, T., Swadlow, H.A., Alonso, J.M. (2003) How changes in arousal affect visual contrast sensitivity. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2003 CD-ROM: Program No. 551.5, 2003.

Martinez, L.M., Alonso, J.M., Hirsch, J.A. (2003) Synaptic structure of receptive fields in the cat’s early visual pathway. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2003 CD-ROM: Program No. 910.19, 2003.

Yeh, C.I., Stoelzel, C.R., Weng, C., Alonso, J.M. (2003) What do cortical cells inherit from their non-linear Y geniculate inputs? Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2003 CD-ROM: Program No. 911.14, 2003.

Stoelzel, C.R., Yeh, C.I. Weng, C., Alonso, J.M. (2002). Different rules of connectivity for different geniculate layers. Society for Neuroscience Abstracts 352.12.

Weng, C., Stoelzel, C.R., Yeh, C.I., Alonso, J.M. (2002). Receptive field size and response latency are correlated within the cat visual thalamus. Society for Neuroscience Abstracts 352.11.

Alonso, J.M., Stoelzel, C.R., Yeh, C.I. (2001). A role for precise spike timing in the lateral geniculate nucleus: detecting stimulus transients. Society for Neuroscience Abstracts, 27, Prog. No. 821.56. 

Yeh, C.I., Stoelzel, C.R., Alonso, J.M. (2001). Two different types of Y cells in the lateral geniculate nucleus? Society for Neuroscience Abstracts, 27, Prog. No. 723.17. 

Hirsch, J.A., Martinez, L.M., Alonso, J.M., Pillai, C., Pierre, C. (2000) Simple and complex inhibitory cells in layer 4 of cat visual cortex. Society for Neuroscience Abstracts, 26: 1083.

Stoelzel, C.R., Yeh, C.I., Bachand, J., Alonso, J.M. (2000) Tight correlated firing between cells in layer C of the cat lateral geniculate nucleus: a comparison with layer A. Soc Neurosci Abstr 26: 1965. 

Veredas, F.J., Alonso, J.M., Vico, F.J. (2000) Exploring networks that generate correlated firing consistent with monosynaptic connections. Soc Neurosci Abstr 26, 1966. 

Yeh, C.I., Stoelzel, C.R., Bachand, J., Alonso, J.M. (2000) Tight correlated firing is scarce between pairs of layer A-layer C cells of the cat lateral geniculate nucleus. Soc Neurosci Abstr 26: 1965. 

Alonso, J.M., Usrey, W.M., Reid, R.C. (1999). Response time-course of simple cells and their geniculate inputs in cat visual cortex. Society for Neuroscience Abstracts 25: 196.

Cechi, G.A., Sigman, M., Alonso, J.M., Martinez, L., Chialvo, D., Magnasco, M.O. (1999) Noise in neurons is message dependent. Society for Neuroscience Abstracts 25: 359.

Martinez, L.M., Reid, R.C., Alonso, J.M., Hirsch, J.A. (1999). The synaptic structure of the simple receptive field. Society for Neuroscience Abstracts 25: 359.

Alonso, J.M., Martinez, L.M. (1998) The generation of complex receptive fields in the superficial layers of the cat visual cortex. Soc Neurosci Abstr 24, 1756.

Alonso JM, Martinez LM (1997) Connectivity between simple cells and complex cells in cat visual cortex. Soc. Neurosci. Abstr. 23:1668.

Hirsch JA, Alonso JM, Reid RC, Martinez LM (1997) Differences between the synaptic responses of first and second order complex cells in cat striate cortex. Soc. Neurosci. Abstr. 23:1668.

Reid RC, Alonso JM, Hendry SHC (1997) S-cone input is relayed to visual cortex from two konio-cellular layers of macaque LGN. Soc. Neurosci. Abstr. 23:13.

Alonso JM (1996) The microcircuitry of complex cells in cat striate cortex. Soc. Neurosci. Abstr. 22: 489.

Dan Y, Alonso JM, Usrey WM, Reid RC (1996) Coding of visual information by precisely correlated spikes in the LGN. Soc. Neurosci. Abstr. 22:1703.

Hirsch JA, Alonso JM, Reid RC, Gallagher CA (1996) Complex cells in layer 6 project to the superficial layers in cat striate cortex. Soc. Neurosci. Abstr. 22: 489.

Usrey WM, Alonso JM, Reid RC (1996) Temporal dependence of the interactions between geniculate inputs to simple cells in cat visual cortex. Soc. Neurosci. Abstr. 22: 1703.

Alonso JM, Atick JJ, Reid RC (1995) The temporal responses of LGN receptive fields studied with white noise. Vis. Sci. Suppl. 36, s. 689.

Alonso JM, Hirsch JA, Reid RC (1995) The intracellular responses produced by moving and static stimuli are well matched in simple cells. Soc. Neurosci. Abstr. 21:21.

Usrey WM, Alonso JM, Reid RC (1995) The interactions between multiple geniculate inputs to simple cells in cat visual cortex. Soc. Neurosci. Abstr. 21:21.

Hirsch JA, Alonso JM, Reid RC (1995) Two dimensional spatial maps of excitation and inhibition in the simple receptive field. Soc. Neurosci. Abstr. 21:21.

Reid RC, Alonso JM, Wiesel TN (1994) Rules determining the monosynaptic connections between LGN cells and simple cells in the cat visual cortex. Soc Neurosci Abstr 20:1476.

Alonso JM, Reid RC (1994) Coupling between neighboring LGN cells: possible implications for simple receptive fields. Soc Neurosci Abstr 20:1476.

Hirsch JA, Alonso JM, Reid RC (1994) Visually evoked calcium action potentials in simple and complex cells in the cat striate cortex. Soc Neurosci Abstr 20:1476.

Sánchez-Vives MV, Hirsch JA, Alonso JM, Reid RC (1994) Synaptic response of complex cells in the cat striate cortex. Soc Neurosci Abstr 20:1476.

Alonso JM, Reid RC, Wiesel TN (1993) Synaptic connectivity between LGN and visual cortex in the cat: cross-correlation and receptive field overlap. Soc Neurosci Abstr 19:424.

Cudeiro J, Rivadulla C, Rodriguez R, Martinez-Conde S, Acuña C, Alonso JM (1993) Direction domain modulation of centre-surround antagonism in the Lateral Geniculate Nucleus (dLGN) of the cat. ENA/SEN Abstract.

Rivadulla C, Cudeiro J, Rodriguez R, Martinez-Conde S, Acuña C, Alonso JM (1993) Nitric Oxide modulates visual processing in the cat Lateral Geniculate Nucleus. ENA/SEN Abstract.

Alonso JM, Cudeiro J, Pérez R, González F, Casas L, Acuña C (1992) Influencia de la capa V del Area 18 sobre la capa V del Area 17 en la corteza visual del gato. CSECF Cordoba.

Alonso JM, Cudeiro J, Pérez R, González F, Casas L, Acuña C (1992) Influence of layer V of visual area 18 of the cat on receptive field properties of cells in layer V of area 17. Eur J Neurosci [Suppl] 5:260 (4150).

Acuña C, Alonso JM, González F, Pérez R, Casas L (1991) Feedback influence of visual area 18 on area 17 cortical cells. II International Meeting on Visual Neuroscience. Granada.

Alonso JM, Pérez R, González F, Acuña C (1991) Functional relationship between visual cortical areas 17 and 18 in the cat. Pflugers Archive. R 185: 113.

González F, Krause F, Pérez R, Alonso JM, Casas L and Acuña C (1991). Cell responses in monkey visual cortex to correlated and uncorrelated random dot stereograms. 14 ENA. Cambridge.

Acuña C, Pérez R, Alonso JM, González F, Krause F, Cudeiro J (1988) Functional relationship between A17 and A18 in cats. International Meeting on Visual Neuroscience, 11-12.

Acuña C, Carregal A, Pérez R, Alonso JM, Cudeiro J, González F (1987) Células complejas (sacádicas y de proyección) en el pulvinar y área parietal 7. Trabajos del Instituto Cajal, LXXVI, 113.

Acuña C, Pérez R, Carregal A, Alonso JM, Cudeiro J, González F (1987) Relación funcional y anatómica entre el pulvinar y el área 7 estudiada en monos activos. XXII Congreso Soc. Esp. C. Fisiol., 278.

Acuña C, Pérez R, Carregal A, Alonso JM, Cudeiro J, González F (1987) Complex cells (sacadic and reaching) in the pulvinar and parietal area 7 of behaving monkeys. Neuroscience, Sup. 22, 219.9

Cudeiro J, Alonso JM, Carregal A, Pérez R, González F, Acuña C (1987) Células de proyección en el LP-Pulvinar y en el área cortical 5a en el mono (Macaca Nemestrina). Trabajos del Instituto Cajal, LXXVI,118.

  •  
  • Pérez R, Alonso JM, Cudeiro J, González F, Krause F, Acuña C (1987) Adrenergic receptors in the visual cortex of the cat. Distribution and functional role. International Meeting on Visual Neuroscience, 10.

Invited Talks

 
  • Baylor College of Medicine (Houston)

  • Brown University (Providence)

  • California Institute of Technology (Los Angeles)

  • City University of New York (Manhattan, New York)

  • City University of New York (Queens, New York)

  • Columbia University (New York), Drexel University (Philadelphia), Cosyne 2008 (Salt Lake City)

  • Harvard Medical School (Boston)

  • Japan Society for Neuroscience (Nagoya),

  • Johns Hopkins University (Maryland),

  • Ludwig-Maximilians-University Munich (Munich, Germany)

  • Mount Sinai School of Medicine (New York)

  • Northwestern University (Evanston, IL)

  • Physiological Society of London (Cambridge, UK)

  • Salk Institute (San Diego)

  • Spanish Society for Neuroscience (Santiago de Compostela, Spain)

  • Spanish Society for Neuroscience (Valladolid, Spain)

  • Spanish Society of Psychiatry (Vigo, Spain)

  • State University of New York (Stonybrook, Long Island)

  • State University of New York (College of Optometry, Manhattan)

  • University College of London (London, UK)

  • University of California (Los Angeles)

  • University of South California (Los Angeles)

  • University of Connecticut (Storrs)

  • University of Malaga (Malaga, Spain)

  • University of Montreal (Montreal, Canada)

  • University of Pennsylvania (Philadelphia)

  • University of Santiago de Compostela (Santiago de Compostela, Spain)

  • Yale University (New Haven, CT)

  • Weill Medical College of Cornell University (New York)

Postdoctoral Fellows

 

Luis M. Martinez.
Associate Professor,
Neuroscience Institute of Alicante, Spain.

Monica Cano Viñas.
Postdoctoral student at Yale University.

Yao Chen.
Assistant Professor
Shanghai Jiao Tong University.

Jianzhong Jin.
Current postdoctoral student

Xiaobing Li.
Current postdoctoral student

Jens Kremkow.
Current postdoctoral student.

PhD and MS Students

 

Francisco J. Veredas (Ph.D.).
Associate Professor,
University of Malaga, Spain.

Carl Stoelzel (M.S.)
Research Scientist,
University of Connecticut.

Chun-I Yeh (Ph.D.)Assistant Professor.
National University of Taiwan

Chong Weng (Ph.D)
Actuarial analyst working in industry.

Yushi Wang (M.D., M.S.)
Current Ph.D. student.

Sanjiv Anand (M.D.)
Medical Resident at SUNY Downstate.

Reza Lashgari (M.D, M.S.)
Current Ph.D. student.

Stanley Komban.
Current Ph.D. student.

Mike Jansen.
Current Ph.D. student.

Undergraduate Research Students

 

Jason Bachand, Graduated May 1999
Catherine Takacs, Graduated May 2000
Lucia Perfetti, Graduated May 2000
Michael Eglinton, Graduated May 2001
Stephanie Hyer, Graduated May 2002
Michael McKee, Graduated May 2001
Monika Pychynska, Graduated May 2001
Eric Rey, Graduated May 2001
Bosko Trputec, Graduated May 2001

Teaching Experience

 
  • Ocular Anatomy and Physiology, Optometry students (2007)

  • Sensation and Perception (University of Connecticut). Undergraduate students (1999-2001)

  • Sensation and Movement (University of Connecticut). Graduate students (2002)

  • Seminars in Behavioral Neuroscience (University of Connecticut). Graduate students (2001-2002)

University Committees

 
  • Institutional Animal Care and Use Committee (IACUC) at The University of Connecticut (1999-2002) and SUNY College of Optometry (2002)

  • Thesis committees at the University of Connecticut, University of Malaga (Spain), Mount Sinai School of Medicine (New York), University College of London (UK) and University of Pennsylvania (Philadelphia)

  • Chairman of the Committee on graduate admissions at SUNY College of Optometry (2005)

  • Dean Search Committee at SUNY College of Optometry (2008), Research Council at SUNY Optometry (2002), Faculty Executive Committee at SUNY Optometry (2007), Strategic Planning Committee at SUNY Optometry (2008), Presidential Inauguration Committee at SUNY Optometry (2008-), Honorary degree committee (2008-)

Grant Reviews

 
  • Arizona Biomedical Research Commission (USA)

  • Biomedical Research Council of Singapore (Singapore)

  • Biotechnology and Biological Sciences Research Council (UK)

  • City University of New York (USA) 

  • National Institutes of Health (USA)

    • Scientific Review IFCN-8 (2003)

    • Scientific Review ZRG1 F02B (2003-2006)

    • Scientific Review SMI (2006)

    • Scientific Review ZRG1-IFCN-B-03M (2007)

    • Scientific Review NEI for K99s (2007)

    • Scientific Review NEI for K08s, K23s, K99s and T32s (2007)

    • Chairman of Scientific Review ZRG1 F02B (2008)

    • Scientific Review NEI LRP (2008)

    • Member of Scientific Review NEI CVP (2008-2012)

  • National Science Foundation (USA)

  • Netherlands Organization for Scientific Research (The Netherlands)

  • Research Foundation at the University of Connecticut (USA)

  • The Israel Science Foundation (Israel)

  • The Wellcome Trust (UK)

Journal Reviews

 

Brain Research, Cerebral Cortex, Current Biology, Experimental Brain Research, Journal of Neurophysiology, Journal of Neuroscience, Journal of Neuroscience Methods, Journal of Vision, Nature, Nature Neuroscience, Neuron, Open Neuroscience Journal, Proceedings of the National Academy of Sciences, Perception, PLoS Biology, PLoS ONE, Progress in Neurobiology, Vision Research, Visual Neuroscience, Science.

Editorial Boards

 
  • Journal of Optometry

  • Thalamus and Related Systems

  • Frontiers in Integrative Neuroscience